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A9062

Adenosine 5′-triphosphate di(tris) salt hydrate

≥95%, Fermentation, powder

Synonym(s):

ATP, 5′-ATP-DiTris

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100 mg
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$65.30
1 g
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$122.00
5 x 1 g
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$519.00
10 g
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$795.00

About This Item

Empirical Formula (Hill Notation):
C10H16N5O13P3 · 2C4H11NO3 · xH2O
CAS Number:
Molecular Weight:
749.45 (anhydrous basis)
MDL number:
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51
Assay:
≥95%
Biological source:
(Fermentation)
Form:
powder
Solubility:
H2O: 50 mg/mL
Storage temp.:
−20°C

$65.30


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Product Name

Adenosine 5′-triphosphate di(tris) salt hydrate, ≥95%

biological source

(Fermentation)

Quality Level

assay

≥95%

form

powder

solubility

H2O: 50 mg/mL

cation traces

Na: ≤0.1%

shipped in

dry ice

storage temp.

−20°C

SMILES string

O.NC(CO)(CO)CO.NC(CO)(CO)CO.Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2C4H11NO3.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;2*5-4(1-6,2-7)3-8;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);2*6-8H,1-3,5H2;1H2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

ZMNHJZFDZFGOFE-MSQVLRTGSA-N

Application

Adenosine 5′-triphosphate di(tris) salt hydrate has been used:
  • to treat cells for Ca2+ influx measurements in stromal interaction molecule 1 knockout (STIM1−/−) mice and in vitro chemotaxis assay for microglial migration
  • supplemented in buffer C for mitochondrial respiratory control assay and complex V activity assay
  • in the inhibition of silver nano particles (AgNPs) on Na+/K+-ATPase activity

Biochem/physiol Actions

Adenosine 5′-triphosphate di(tris) salt dehydrate is useful in applications that require the absence of metals.
Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.
P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems

Disclaimer

Unstable: For maximum stability, store as frozen solution at pH 3.5 to 6.8.

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This Item
A2383A3377A2647
biological source

(Fermentation)

biological source

microbial

biological source

microbial

biological source

natural (organic)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

crystalline

form

powder

assay

≥95%

assay

≥99%

assay

≥97% (HPLC)

assay

≥93% (HPLC)

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

dry ice


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Silver nanoparticle-protein interactions in intact rainbow trout gill cells.
Yue Y, et al.
Environmental science. Nano, 3(5), 1174-1185 (2016)
Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart.
McLaughlin KL, et al.
Biochemical and biophysical research communications, 504(4), 742-748 (2018)
UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1-/- Microglia in Vitro and in Vivo.
Lim HM, et al.
Mediators of Inflammation, 2017 (2017)



Global Trade Item Number

SKUGTIN
A9062-100MG04061833258538
A9062-1G04061835553693
A9062-10G04061833329108
A9062-5X1G04061833423943

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