A9891
7-Amino-4-methylcoumarin
chromophore for enzyme substrates, fluorogenic, ≥98% (HPLC), powder
Synonym(s):
Coumarin 120
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
250 mg | Available to ship TODAYfromMILWAUKEE | $149.00 |
500 mg | Available to ship TODAYfromMILWAUKEE | $284.00 |
1 g | Available to ship TODAYfromMILWAUKEE | $462.00 |
About This Item
$149.00
Available to ship TODAYDetails
Product Name
7-Amino-4-methylcoumarin, Chromophore for substrates
Quality Segment
description
chromophore for enzyme substrates
assay
≥98% (HPLC)
form
powder
mp
223-226 °C (lit.)
solubility
acetone: 10 mg/mL, clear, colorless to yellow
fluorescence
λex 365 nm; λem 440 nm in ethanol(lit.)
storage temp.
2-8°C
SMILES string
CC1=CC(=O)Oc2cc(N)ccc12
InChI
1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
InChI key
GLNDAGDHSLMOKX-UHFFFAOYSA-N
Application
- to determine cathepsin B like- activity
- as a substrate for leucine aminopeptidase (LAP)
- in chymotryptic assay
- as a standard to detect the activation of caspase-3 during
- sanguinarine-induced damage
- protection by human DEAD-box DDX3
Biochem/physiol Actions
Preparation Note
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| description Chromophore for substrates | description Reagent used to prepare fluorogenic 7-amido-4-methylcoumarin (AMC) based substrates for the detection of proteolytic enzyme activity. | description 99% | description AldrichCPR |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay 99% | assay - |
| solubility acetone: 10 mg/mL, clear, colorless to yellow | solubility DMSO: 10 mg/mL, DMF: soluble, acetone: 10 mg/mL | solubility - | solubility - |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level - |
| form powder | form solid | form solid | form solid |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
| fluorescence λex 365 nm; λem 440 nm in ethanol(lit.) | fluorescence λex 365-380 nm, λem 430-460 nm | fluorescence - | fluorescence - |
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
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