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B1401

Bradykinin Fragment 1-5

≥97% (HPLC)

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1 mg

Available to ship TODAYfromMILWAUKEE

$89.30
$75.90
5 mg

Available to ship TODAYfromMILWAUKEE

$314.00

About This Item

Empirical Formula (Hill Notation):
C27H40N8O6
CAS Number:
23815-89-6
Molecular Weight:
572.66
NACRES:
NA.32
PubChem Substance ID:
24891591
UNSPSC Code:
12352200
MDL number:
MFCD00076260
Form:
powder
Assay:
≥97% (HPLC)

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Quality Segment

200

assay

≥97% (HPLC)

form

powder

UniProt accession no.

P01042

storage temp.

−20°C

SMILES string

NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(O)=O

InChI

1S/C27H40N8O6/c28-18(9-4-12-31-27(29)30)24(38)35-14-6-11-21(35)25(39)34-13-5-10-20(34)23(37)32-16-22(36)33-19(26(40)41)15-17-7-2-1-3-8-17/h1-3,7-8,18-21H,4-6,9-16,28H2,(H,32,37)(H,33,36)(H,40,41)(H4,29,30,31)

InChI key

USSUMSBPLJWFSZ-UHFFFAOYSA-N

Gene Information

human ... KNG1 (includes EG:3827)

Biochem/physiol Actions

The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
B1901I3400K1632
Bradykinin Fragment 1-5 ≥97% (HPLC)

Sigma-Aldrich

B1401

Bradykinin Fragment 1-5

Bradykinin Fragment 2-9 ≥97% (HPLC)

Sigma-Aldrich

B1901

Bradykinin Fragment 2-9

Interferon-γ-Inducible Protein-10 human ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

Sigma-Aldrich

I3400

Interferon-γ-Inducible Protein-10 human

Kininogen high molecular weight, Two Chain from human plasma lyophilized powder

Sigma-Aldrich

K1632

Kininogen high molecular weight, Two Chain from human plasma

description

≥97% (HPLC)

description

≥97% (HPLC)

description

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

description

lyophilized powder

assay

≥97% (HPLC)

assay

≥97% (HPLC)

assay

≥97% (SDS-PAGE)

assay

-

form

powder

form

powder

form

lyophilized powder

form

lyophilized powder

UniProt accession no.

P01042

UniProt accession no.

P01042

UniProt accession no.

P01579

UniProt accession no.

P01042

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Gene Information

human ... KNG1 (includes EG:3827)(3827)

Gene Information

human ... KNG1 (includes EG:3827)(3827)

Gene Information

human ... CXCL10(3627)

Gene Information

human ... KNG1(3827), KNG1 (includes EG:3827)(3827)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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