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B3383

Benzidine dihydrochloride

≥99% (titration)

Synonym(s):

4,4′-Diaminobiphenyl dihydrochloride

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1 g

Available to ship TODAYfromMILWAUKEE

$526.00
5 g

Available to ship TODAYfromMILWAUKEE

$285.00
10 g

Available to ship TODAYfromMILWAUKEE

$526.00

About This Item

Empirical Formula (Hill Notation):
C12H12N2 · 2HCl
CAS Number:
Molecular Weight:
257.16
UNSPSC Code:
12352116
NACRES:
NA.25
PubChem Substance ID:
EC Number:
208-519-6
Beilstein/REAXYS Number:
3914846
MDL number:
Assay:
≥99% (titration)
Form:
powder
Quality level:

$526.00


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Quality Level

assay

≥99% (titration)

form

powder

SMILES string

Cl[H].Cl[H].Nc1ccc(cc1)-c2ccc(N)cc2

InChI

1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H

InChI key

RUAXWVDEYJEWRY-UHFFFAOYSA-N

Application

Benzidine (4,4′-Diaminobiphenyl) is an environmental genotoxin that posses increased risks of cancer to exposed people. Benzidine may be used as a reference material in procedures that analyze for benzidine. Benzidine can be used in studies on its mechanisms of genotoxicity.

Biochem/physiol Actions

Tumor initiator in mammary glands of experimental animal.[1]

Disclaimer

Cancer suspect agent.

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form

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assay

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assay

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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Articles

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.


K C Morton et al.
Carcinogenesis, 2(8), 747-752 (1981-01-01)
To evaluate the role of metabolism in benzidine (BZ) carcinogenesis, BZ and 2 or its metabolites, N,N'-diacetylbenzidine and N-hydroxy-N,N'-diacetylbenzidine (NOHDABZ), were given by i.p. injection to female CD rats twice weekly for 4 weeks beginning at 30 days of age.
Yan Cao et al.
Stem cells and development, 24(22), 2660-2673 (2015-07-17)
Autophagy is required for hematopoietic stem cell multilineage differentiation, but the underlying mechanism is unknown. Using a conditional mouse model and human leukemia cells, we uncovered a mechanistic link between autophagy and hematopoietic stem cell differentiation. Loss of autophagy in
Juliana Piva de Almeida et al.
Forensic science international, 206(1-3), 58-61 (2010-07-21)
Bloodstains often constitute the major physical evidence in crime investigation. Diluted blood invisible to the naked eye can be detected through presumptive tests however such tests can damage samples and prevent further processing such as DNA analysis. In this study



Global Trade Item Number

SKUGTIN
B3383-5G04061833427804
B3383-10G04061833427750
B3383-1G04061833427798

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