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B4813

BGP-15

≥98% (HPLC)

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$199.00
25 mg

Available to ship TODAYfromMILWAUKEE

$799.00

About This Item

Empirical Formula (Hill Notation):
C14H22N4O2· 2HCl
CAS Number:
Molecular Weight:
351.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$199.00


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Quality Segment

assay

≥98% (HPLC)

form

solid

solubility

deionized water: 28 mg/mL

storage temp.

−20°C

SMILES string

Cl.Cl.N\C(=N/OCC(O)CN1CCCCC1)c2cccnc2

InChI

1S/C14H22N4O2.2ClH/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18;;/h4-6,9,13,19H,1-3,7-8,10-11H2,(H2,15,17);2*1H

InChI key

ISGGVCWFTPTHIX-UHFFFAOYSA-N

General description

BGP-15 is a hydroxylamine derivative, which has cytoprotective and neuroprotective properties. It reduces phospho- c-Jun N-terminal kinase (pJNK) and p38 stress signalling. BGP-15 also stimulates non-specific serine/threonine protein kinase (AKT) and insulin-like growth factor 1 receptor (IGFR1) protective signalling. BGP-15 functions as an insulin sensitizer in an olanzapine-induced metabolic disorder. It protects cells against cell death and enhances the expression of heat shock protein (HSP). BGP-15 might be used to treat heart failure (HF) and atrial fibrillation (AF).

Application

BGP-15 has been used to study its influence on proteasomal degradation of missense dystrophins.

Biochem/physiol Actions

BGP-15 is PARP inhibitor, HSP72 activator.
BGP-15 is PARP inhibitor, HSP72 activator.

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This Item
G9422G5422
description

≥98% (HPLC)

description

BioUltra, suitable for cell culture, suitable for plant cell culture, ≥99% (titration)

description

≤1.0 mol % L-α-isomer

form

solid

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥99% (titration)

assay

-

Quality Level

100

Quality Level

400

Quality Level

300

storage temp.

−20°C

storage temp.

-

storage temp.

-

solubility

deionized water: 28 mg/mL

solubility

water: soluble

solubility

water: 50 mg/mL, clear, colorless


Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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