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B8684

Bambuterol hydrochloride

>98% (HPLC), β-adrenoceptor agonist, powder

Synonym(s):

Dimethylcarbmic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester

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10 mg

Available to ship TODAYfromMILWAUKEE

$145.00
50 mg

Available to ship TODAYfromMILWAUKEE

$537.00
$456.45

About This Item

Linear Formula:
C18H29N3O5 · HCl
CAS Number:
81732-46-9
Molecular Weight:
403.90
UNSPSC Code:
12352200
PubChem Substance ID:
329773137
NACRES:
NA.77
MDL number:
MFCD03427293
Assay:
>98% (HPLC)
Form:
powder
Quality level:
100
Storage condition:
desiccated

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Product Name

Bambuterol hydrochloride, >98% (HPLC), powder

Quality Level

100

assay

>98% (HPLC)

form

powder

storage condition

desiccated

color

off-white

solubility

H2O: soluble ~33 mg/mL

originator

AstraZeneca

SMILES string

Cl.CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C

InChI

1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H

InChI key

LBARATORRVNNQM-UHFFFAOYSA-N

General description

Bambuterol is present in various tissues, like , intestine, lungs, liver and heart. It is also found in serum.

Application

Bambuterol hydrochloride has been used as a β2-adrenergic receptor (β2-AR) agonist to study its effects on graft versus host disease (GVHD) while preserving the graft-versus-tumor (GvT) effect. It has also been used in the preparation of bambuterol-poly vinyl chloride (Bb-PVC) membrane sensors for the determination of bambuterol in the pharmaceutical dosage form.

Biochem/physiol Actions

β-adrenoceptor agonist; bronchodilator; anti-asthmatic; terbutaline prodrug
Bambuterol hydrochloride is used for prophylaxis and also to treat chronic bronchitis and chronic asthma in pediatrics.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Bambuterol hydrochloride >98% (HPLC), powder

Sigma-Aldrich

B8684

Bambuterol hydrochloride

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B0250000

Bambuterol hydrochloride

Mabuterol hydrochloride VETRANAL®, analytical standard

Supelco

32573

Mabuterol hydrochloride

Brombuterol hydrochloride VETRANAL®, analytical standard

Supelco

94972

Brombuterol hydrochloride

assay

>98% (HPLC)

assay

-

assay

-

assay

≥99.0% (HPLC)

form

powder

form

-

form

-

form

-

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

solubility

H2O: soluble ~33 mg/mL

solubility

-

solubility

-

solubility

-

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

color

off-white

color

-

color

-

color

-

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000223822
0000223821
0000223822
0000223821
0000192062

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Articles

DISCOVER Bioactive Small Molecules for Neuroscience

DISCOVER Bioactive Small Molecules for Neuroscience

Hemn Mohammadpour et al.
JCI insight, 5(12) (2020-05-22)
Acute graft versus host disease (aGvHD) remains a major impediment to successful allogeneic hematopoietic cell transplantation (allo-HCT). To solve this problem, a greater knowledge of factors that regulate the differentiation of donor T cells toward cytotoxic cells or Tregs is
PVC membrane sensors for potentiometric determination of bambuterol in pharmaceutical formulation
Ezzeldin E, et al.
International Journal of Electrochemical Science, 7(11), 10570-10581 (2012)
Yejin Jang et al.
Viruses, 12(5) (2020-05-30)
Influenza A virus, one of the major human respiratory pathogens, is responsible for annual seasonal endemics and unpredictable periodic pandemics. Despite the clinical availability of vaccines and antivirals, the antigenic diversity and drug resistance of this virus makes it a
View All Related Papers

Global Trade Item Number

SKUGTIN
B8684-50MG04061832079387
B8684-10MG04061832088839

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