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C3649

CHAPSO

≥98%

Synonym(s):

3-([3-Cholamidopropyl]dimethylammonio)-2-hydroxy-1-propanesulfonate

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Size/SKUAvailabilityPrice
500 mg

Available to ship TODAYfromMILWAUKEE

$198.00
1 g

Estimated to ship onAugust 12, 2026fromMILWAUKEE

$198.00
5 g

Estimated to ship onAugust 12, 2026fromMILWAUKEE

$654.00
25 g

Available to ship TODAYfromMILWAUKEE

$2,420.00

About This Item

Empirical Formula (Hill Notation):
C32H58N2O8S
CAS Number:
Molecular Weight:
630.88
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5842642

$198.00


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biological source

animal

Quality Segment

description

zwitterionic

assay

≥98%

form

powder

mol wt

micellar avg mol wt 7000

aggregation number

11

technique(s)

protein quantification: suitable

impurities

≤5% Water (Karl Fischer)

conductivity

≤100 μmho per cm at 24 °C (0.5 M aqueous solution)

CMC

8 mM (20-25°C)

mp

184-186 °C (lit.)

transition temp

cloud point 90 °C

solubility

water: soluble 10 g/L at 20 °C

SMILES string

[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCC[N+](C)(C)CC(O)CS([O-])(=O)=O

InChI

1S/C32H58N2O8S/c1-20(7-10-29(39)33-13-6-14-34(4,5)18-23(36)19-43(40,41)42)24-8-9-25-30-26(17-28(38)32(24,25)3)31(2)12-11-22(35)15-21(31)16-27(30)37/h20-28,30,35-38H,6-19H2,1-5H3,(H-,33,39,40,41,42)/t20-,21+,22-,23?,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChI key

GUQQBLRVXOUDTN-XOHPMCGNSA-N

General description

CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group.

Application

CHAPSO has been used:
  • in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins
  • in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range
  • as a mixture with dilauroyl phosphatidylcholine (DLPC) in solid-state nuclear magnetic resonance (NMR) technique to study membrane-associated proteins
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

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This Item
C4695220202C3023
description

≥98%

description

BioXtra

description

Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.

description

≥98% (HPLC)

assay

≥98%

assay

≥98.0% (TLC)

assay

>98% (TLC)

assay

≥98% (HPLC)

technique(s)

protein quantification: suitable

technique(s)

-

technique(s)

-

technique(s)

dialysis: suitable, electrophoresis: suitable

form

powder

form

powder

form

solid

form

powder

aggregation number

11

aggregation number

11

aggregation number

11

aggregation number

-

biological source

animal

biological source

-

biological source

-

biological source

bovine bile

CMC

8 mM (20-25°C)

CMC

8 mM (20-25°C), 8 mM (micellar weight =9960)

CMC

8 mM

CMC

8 mM


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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