C5732
CA-074
synthetic (organic), ≥98% (HPLC), cathepsin B inhibitor, powder
Synonym(s):
(L-3-trans-(Propylcarbamyl)oxirane-2-carbonyl)-
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $554.00 |
About This Item
Product Name
CA-074, ≥98% (HPLC)
biological source
synthetic (organic)
Quality Segment
assay
≥98% (HPLC)
form
powder
solubility
methanol: 1 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H]([C@H](C)CC)C(=O)N2CCC[C@H]2C(O)=O
InChI
1S/C18H29N3O6/c1-4-8-19-15(22)13-14(27-13)16(23)20-12(10(3)5-2)17(24)21-9-6-7-11(21)18(25)26/h10-14H,4-9H2,1-3H3,(H,19,22)(H,20,23)(H,25,26)/t10?,11-,12-,13-,14-/m0/s1
InChI key
ZEZGJKSEBRELAS-NSIINPIOSA-N
Application
- to study its effect on pseudotyped viruses bearing S proteins harboring R642M and N714K using HeLa cells
- to determine the role of autophagy in glucose deprivation (GD)-induced damage
- to study its effects on neuronal function upon exposure to His-cathepsin B (CATB)
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥99% (TLC) | description CA-074, also referenced under CAS 134448-10-5, modulates the biological activity of cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. | description CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B. |
| assay ≥98% (HPLC) | assay ≥99% (TLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form solid | form solid | form solid |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility methanol: 1 mg/mL, clear, colorless | solubility - | solubility DMSO: 10 mg/mL | solubility DMSO: 10 mg/mL |
| biological source synthetic (organic) | biological source synthetic (organic) | biological source - | biological source - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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