Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

C7555

Concanavalin A from Canavalia ensiformis (Jack bean)

agarose conjugate, Type VI, saline suspension

Synonym(s):

ConA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mL

Available to ship TODAYfromMILWAUKEE

$186.00
25 mL
Check Cart for Availability
$632.00
100 mL

Available to ship TODAYfromMILWAUKEE

$1,750.00

About This Item

NACRES:
NA.32
UNSPSC Code:
12161501
Form:
saline suspension
Biological source:
Canavalia ensiformis

$186.00

Available to ship TODAYDetails

​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

Canavalia ensiformis

Quality Segment

200

conjugate

agarose conjugate

type

Type VI

form

saline suspension

extent of labeling

≥15 mg concanavalin A protein per mL

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

storage temp.

2-8°C

General description

Concanavalin A (Con A), isolated from Jack beans (Canavalia ensiformis), is a mannose or glucose specific-binding lectin. The lectin is a tetramer and each subunit possesses a saccharide-binding site. Con A can be isolated by affinity chromatography with dextrans.

Application

Used for the purification of glycoproteins containing mannose
Concanavalin A (Con A) has been used for enzyme immobilization.

Biochem/physiol Actions

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
Concanavalin A (Con A) is a T cell mitogen that can activate the lymphocytes.
Con A can induce tumor cell death through autophagy.

Physical form

Suspension in 1.0 M NaCl + 0.1 M potassium phosphate, pH 6.0, with 1 mM CaCl2, 1 mM MgCl2 and 1 mM MnCl2 containing preservative

Analysis Note

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
C9017C5275C7642
Concanavalin A from Canavalia ensiformis (Jack bean) agarose conjugate, Type VI, saline suspension

Sigma-Aldrich

C7555

Concanavalin A from Canavalia ensiformis (Jack bean)

Concanavalin A from Canavalia ensiformis (Jack bean) Sepharose™ conjugate, buffered aqueous suspension

Sigma-Aldrich

C9017

Concanavalin A from Canavalia ensiformis (Jack bean)

Concanavalin A from Canavalia ensiformis (Jack bean) Type IV-S, lyophilized powder, aseptically processed, BioReagent, suitable for cell culture

Sigma-Aldrich

C5275

Concanavalin A from Canavalia ensiformis (Jack bean)

Concanavalin A from Canavalia ensiformis (Jack bean) FITC conjugate, Type IV, lyophilized powder

Sigma-Aldrich

C7642

Concanavalin A from Canavalia ensiformis (Jack bean)

description

agarose conjugate, Type VI, saline suspension

description

Sepharose™ conjugate, buffered aqueous suspension

description

Type IV-S, lyophilized powder, aseptically processed, BioReagent, suitable for cell culture

description

FITC conjugate, Type IV, lyophilized powder

biological source

Canavalia ensiformis

biological source

Canavalia ensiformis

biological source

-

biological source

Canavalia ensiformis

form

saline suspension

form

buffered aqueous suspension

form

lyophilized powder

form

lyophilized powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

matrix

cross-linked 4% beaded agarose

matrix

Sepharose 4B

matrix

-

matrix

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

conjugate

agarose conjugate

conjugate

Sepharose™ conjugate

conjugate

-

conjugate

FITC conjugate

Still not finding the right product?

Explore all of our products under Concanavalin A from Canavalia ensiformis (Jack bean)

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

10 - Combustible liquids

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters