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D4876

Dextran from Leuconostoc mesenteroides

average mol wt 150,000

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50 g

Available to ship TODAYfromMILWAUKEE

$122.00
100 g

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$206.00
500 g

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$854.00
1 kg

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$1,480.00

About This Item

Linear Formula:
(C6H10O5)n
CAS Number:
9004-54-0
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
232-677-5
MDL number:
MFCD00130935

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biological source

bacterial (Leuconostoc mesenteroides)

Quality Level

200

form

powder

optical activity

[α]/D 199°

mol wt

average mol wt 150,000

color

white

solubility

H2O: soluble 20 mg/mL

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

Application

Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants and physical structure components.[1] Dextrans may be used as long hydrophilic spacer arms to improve the performance (freedom of movement) of conjugated/bound proteins. Dextrans may be derivatized for use in biosensor systems.[2] Dextran 150 may be used to study iron delivery to cells, cell membrane permeabilization and red blood cell aggregation.
Use of dextrans as long and hydrophilic spacer arms improves the performance of immobilized proteins acting on macromolecules.

Preparation Note

With the exception of the highest MW dextran, D5501 (MW range = 5 million to 40 million), dextrans are very water soluble. Sigma tests the solubility of dextrans at concentrations generally exceeding 30 mg/ml in water. Dextrans are also freely soluble in DMSO, formamide, ethylene glycol, and glycerol. Neutral-aqueous dextran solutions can be sterilized by autoclaving at 110-115oC for 30 to 45 minutes. Dextran can be hydrolyzed by strong acids at high temperatures. The terminal reducing end group of dextran can be oxidized in alkaline solutions.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

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This Item
D3759D882131416
Dextran from Leuconostoc mesenteroides average mol wt 150,000

Sigma-Aldrich

D4876

Dextran from Leuconostoc mesenteroides

Dextran from Leuconostoc mesenteroides average mol wt 48,000-90,000

Sigma-Aldrich

D3759

Dextran from Leuconostoc mesenteroides

Dextran from Leuconostoc mesenteroides average mol wt 60,000-76,000

Sigma-Aldrich

D8821

Dextran from Leuconostoc mesenteroides

Dextran from Leuconostoc mesenteroides analytical standard, Mw 1,000

Supelco

31416

Dextran from Leuconostoc mesenteroides

biological source

bacterial (Leuconostoc mesenteroides)

biological source

bacterial (Leuconostoc mesenteroides)

biological source

bacterial (Leuconostoc mesenteroides)

biological source

-

solubility

H2O: soluble 20 mg/mL

solubility

H2O: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

solubility

water: 100 mg/mL at 25 °C, colorless to faintly yellow

solubility

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

powder

form

powder

form

powder

form

-

color

white

color

white

color

white to off-white

color

-

mol wt

average mol wt 150,000

mol wt

average mol wt 48,000-90,000

mol wt

average mol wt 60,000-76,000

mol wt

Mn ~1,000, Mp ~1,100, Mw ~1,300

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000552383
0000541956
0000541957
0000541958
0000541956

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Protocols

Dextran

Dextran polymer details: composed mainly of alpha-D-(1-6) linkages with varied branch lengths.

Articles

Pharmaceutical Research Applications of Carbohydrates and Polysaccharides

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Carbohydrates as Versatile Enablers of Advanced Drug Delivery Systems

Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.

Related Content

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Product Information Sheet - D4876
Mengyun Lia et al.
Archives of animal nutrition, 65(6), 477-485 (2012-01-20)
Iron (Fe) is an essential and important trace element for animals. In order to study its metabolism and relationship with hepcidin, piglet models of Fe-deficiency and Fe-overload were established by intramuscular injection with different doses of Fe-dextran (150 mg Fe/ml)
Scott A Myers et al.
Experimental neurology, 256, 25-38 (2014-04-03)
CD36 is a pleiotropic receptor involved in several pathophysiological conditions, including cerebral ischemia, neurovascular dysfunction and atherosclerosis, and recent reports implicate its involvement in the endoplasmic reticulum stress response (ERSR). We hypothesized that CD36 signaling contributes to the inflammation and
Elizabeth M Bradshaw et al.
Nature neuroscience, 16(7), 848-850 (2013-05-28)
In our functional dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) risk allele was associated with greater cell surface expression of CD33 in the monocytes (t50 = 10.06, P(joint) = 1.3 × 10(-13)) of young
View All Related Papers

Global Trade Item Number

SKUGTIN
D4876-100G04061833033050
D4876-500G04061833585771
D4876-50G04061833585788
D4876-1KG04061826754269

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