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D6196

Dimebon dihydrochloride hydrate

≥98% (HPLC)

Synonym(s):

2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate, Dimebolin dihydrochloride hydrate, Dimeboline dihydrochloride hydrate, Dimebone dihydrochloride hydrate

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Size/SKUAvailabilityPrice
5 mg
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$169.00

About This Item

Empirical Formula (Hill Notation):
C21H25N3 · 2HCl · xH2O
CAS Number:
Molecular Weight:
392.37 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$169.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

H2O: ≥10 mg/mL

storage temp.

2-8°C

SMILES string

O.Cl.Cl.CN1CCc2c(C1)c3cc(C)ccc3n2CCc4ccc(C)nc4

InChI

1S/C21H25N3.2ClH.H2O/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17;;;/h4-7,12-13H,8-11,14H2,1-3H3;2*1H;1H2

InChI key

QQHQMWVYYVVAOV-UHFFFAOYSA-N

Biochem/physiol Actions

Mechanism of neuroprotection and cognition enhancement is not certain, but Dimebon blocks both cholinesterase and the NMDA receptor simultaneously and also appears to block the action of neurotoxic β-amyloid proteins and inhibit L-type calcium channels, and may exert a neuroprotective effect by blocking a novel target that involves mitochondrial pores.

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
63724684878
description

≥98% (HPLC)

description

nanopowder (spherical, porous), 5-20 nm particle size (TEM), 99.5% trace metals basis

description

purum p.a., acid purified, sand

assay

≥98% (HPLC)

assay

99.5% trace metals basis

assay

-

form

powder

form

nanopowder (spherical, porous)

form

sand

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

2-8°C

storage temp.

-

storage temp.

-

solubility

H2O: ≥10 mg/mL

solubility

-

solubility

-

color

white to off-white

color

-

color

-


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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