There are currently two Hammerstein versions of Casein available, E0789 and 1.02242. Neither of these products are tested according to the JP.
E0789
Casein, Hammarsten bovine
Synonym(s):
Casein from bovine milk
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 500 g | Check Cart for Availability | $249.00 | |
| 5 kg | Check Cart for Availability | $1,150.00 |
About This Item
Form:
powder
Assay:
>90% dry basis
Biological source:
bovine milk (Hammarsten)
$249.00
Check Cart for Availability
biological source
bovine milk (Hammarsten)
Quality Level
assay
>90% dry basis
form
powder
technique(s)
enzyme immunoassay: suitable
mp
280 °C (dec.) (lit.)
storage temp.
room temp
SMILES string
[P](=O)(OCC(NC(=O)C(NC(=O)C(N)Cc1ccccc1)CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(C(O)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C
InChI
1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)
InChI key
BECPQYXYKAMYBN-UHFFFAOYSA-N
Gene Information
bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099), CSN3(281728)
General description
Casein is an amphiphilic protein.
Casein, a phosphoprotein, is the principal protein component of milk which is almost entirely expressed in the lactating mammary gland.[1] In bovine milk they are classified according to their calcium sensitivity: αs1-, αs2-, and β-caseins precipitate in the presence of calcium; whereas κ-casein remains in solution. [2]
Application
Casein, Hammarsten bovine has been used as a substrate for Aplysia californica calpain to study its activity.[3]
The product is useful as a protease substrate.
Biochem/physiol Actions
Casein is useful in food industries and non-food applications. It has the property for emulsification, foam formation, and stabilization, water-binding, and gelation. Casein is also considered heat and acid-stable.
Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.
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This Item | |||
|---|---|---|---|
| assay >90% dry basis | assay - | assay - | assay - |
| biological source bovine milk (Hammarsten) | biological source bovine milk | biological source bovine milk | biological source - |
| technique(s) enzyme immunoassay: suitable | technique(s) activity assay: suitable, electrophoresis: suitable, immunocytochemistry: suitable | technique(s) activity assay: suitable, electrophoresis: suitable, immunocytochemistry: suitable | technique(s) - |
| form powder | form liquid | form powder | form - |
| Gene Information bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099), CSN3(281728) | Gene Information bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099), CSN3(281728) | Gene Information bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099) | Gene Information - |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. - |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
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Margaret H Hastings et al.
PloS one, 12(10), e0186646-e0186646 (2017-10-21)
Calpains are a family of intracellular proteases defined by a conserved protease domain. In the marine mollusk Aplysia californica, calpains are important for the induction of long-term synaptic plasticity and memory, at least in part by cleaving protein kinase Cs
Krisztina Nagy et al.
The Journal of biological chemistry, 285(50), 38811-38817 (2010-10-06)
The possible mechanism of casein aggregation and micelle buildup was studied in a new approach by letting α-casein adsorb from low concentration (0.1 mg·ml(-1)) solutions onto the charged surfaces of polyelectrolyte films. It was found that α-casein could adsorb onto
Bovine beta-casein: Isolation, properties and functionality. A review
Atamer Z, et al.
International dairy journal, 66, 115-125 (2017)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| E0789-500G | 04061833601266 |
| E0789-5KG | 04061833619735 |
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製薬会社で医薬品の品質試験を行なっている者です。このカゼイン（Hammerstein）において、日局等の公定書に基づいて赤外吸収スペクトル測定法の臭化カリウム錠剤法の試験を実施した実績がありますでしょうか。もしなければ、実施実績のある他のカゼイン（Hammerstein）製品の取扱いはございますでしょうか。ご回答お願いいたします。
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