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F3422

Flt-3/Flk-2 ligand human

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE and HPLC)

동의어(들):

FL

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팩 크기SKU재고 정보가격 (VAT 별도)
5 μg

오늘 배송 가능재고 수량 조회Seoul Warehouse South Korea

₩491,768

제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:

₩491,768


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biological source

human

Quality Level

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

potency

≤1.0 ng/mL

mol wt

17.6 kDa

packaging

pkg of 5 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... FLT3(2322)

General description

Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.

Biochem/physiol Actions

Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.

Physical form

Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS.

Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.

유사한 품목 비교

전체 비교 보기

차이점 표시

1 of 1

이 품목
SRP0349H5416SRP3198
technique(s)

cell culture | mammalian: suitable

technique(s)

activity assay: suitable, inhibition assay: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

assay

≥98% (SDS-PAGE and HPLC)

assay

≥80% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

recombinant

expressed in E. coli

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in HEK 293 cells

recombinant

expressed in E. coli

biological source

human

biological source

human

biological source

human

biological source

mouse

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

-

form

lyophilized powder

form

aqueous solution

form

lyophilized powder

form

lyophilized


저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문


문서

Read article on hematopoietic cytokines and hematopoiesis

관련 콘텐츠

Instructions


R Namikawa et al.
Stem cells (Dayton, Ohio), 14(4), 388-395 (1996-07-01)
The biological activities of the ligand for the Flk2/Flt3 receptor tyrosine kinase (FL) on human hematopoietic cells are reviewed. In in vitro studies, FL shows relatively few effects by itself on the proliferation and differentiation of hematopoietic cells, but exhibits
H G Drexler et al.
Leukemia & lymphoma, 33(1-2), 83-91 (1999-04-08)
FLT3 ligand (FL) acting through its tyrosine kinase receptor FLT3 has pleiotropic and potent effects on hematopoietic cells. The well-described involvement of this ligand-receptor pair in physiological hematopoiesis raised the question whether FL and FLT3 also play a role in
Lyman, S., et al. et al.
The Cytokine Handbook, 727-727 (1998)



국제 무역 품목 번호

SKUGTIN
F3422-5UG04061833613924

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