Key Documents

View All Documentation

Flt-3/Flk-2 ligand human

Name: Flt-3/Flk-2 ligand human
Brand: SIGMA

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE and HPLC)

Synonym(s):

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

UNSPSC Code:

51111800

NACRES:

NA.32

MDL number:

MFCD01093789

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

human

Quality Segment

100

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

potency

≤1.0 ng/mL

mol wt

17.6 kDa

packaging

pkg of 5 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P36888

storage temp.

−20°C

Gene Information

human ... FLT3(2322)

Description

General description

Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.

Biochem/physiol Actions

Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.

Physical form

Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS.

Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	SRP0349	SRP3044	H5416
Sigma-Aldrich F3422 Flt-3/Flk-2 ligand human	Sigma-Aldrich SRP0349 Flt3 active human	Sigma-Aldrich SRP3044 Flt-3 Ligand human	Sigma-Aldrich H5416 FLT3 Ligand human
assay ≥98% (SDS-PAGE and HPLC)	assay ≥80% (SDS-PAGE)	assay ≥98% (HPLC), ≥98% (SDS-PAGE)	assay ≥95% (SDS-PAGE)
technique(s) cell culture \| mammalian: suitable	technique(s) activity assay: suitable, inhibition assay: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
biological source human	biological source human	biological source human	biological source human
recombinant expressed in E. coli	recombinant expressed in baculovirus infected Sf9 cells	recombinant expressed in E. coli	recombinant expressed in HEK 293 cells
Quality Level 100	Quality Level -	Quality Level -	Quality Level 100
form lyophilized powder	form aqueous solution	form lyophilized	form lyophilized powder

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.