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F7932

Famciclovir

≥98% (HPLC)

Synonym(s):

2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate ester, BRL 42810

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Size/SKUAvailabilityPrice
50 mg

Available to ship TODAYfromMILWAUKEE

$400.00

About This Item

Empirical Formula (Hill Notation):
C14H19N5O4
CAS Number:
104227-87-4
Molecular Weight:
321.33
NACRES:
NA.77
PubChem Substance ID:
329799767
UNSPSC Code:
12352200
MDL number:
MFCD00866964
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated

$400.00

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Quality Segment

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

solubility

DMSO: ≥10 mg/mL

originator

Novartis

storage temp.

2-8°C

SMILES string

CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O

InChI

1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)

InChI key

GGXKWVWZWMLJEH-UHFFFAOYSA-N

Application

Famciclovir is used in herpes virus infections and hepatitis B drug development research. It may be used as a reference compound. Famciclovir may be used to study the factors that control its conversion into penciclovir and other metabolites.

Biochem/physiol Actions

Famciclovir is an Antiviral; Guanine analog used to treat herpesvirus infections.
Famciclovir is an antiretroviral guanosine analog used to treat herpesvirus infections and hepatitis B. Famciclovir is rapidly converted to penciclovir. Viral thymidine kinase phosphorylates penciclovir to a monophosphate form that celular kinases convert in turn to penciclovir triphosphate. Penciclovir triphosphate competitively inhibits viral DNA polymerase and thus viral replication. Prolonged administration can lead to resistance; it is often manifested as selection of pre-existing resistant strains with mutations in the reverse transcriptase domain of the DNA polymerase gene.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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This Item
PHR16961269174D6946
Famciclovir ≥98% (HPLC)

Sigma-Aldrich

F7932

Famciclovir

Famciclovir Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1696

Famciclovir

USP

USP

1269174

Famciclovir Related Compound A

(R)-DRF053 hydrochloride hydrate ≥98% (HPLC)

Sigma-Aldrich

D6946

(R)-DRF053 hydrochloride hydrate

description

≥98% (HPLC)

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

United States Pharmacopeia (USP) Reference Standard

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

assay

-

assay

≥98% (HPLC)

form

solid

form

-

form

-

form

powder

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

DMSO: ≥10 mg/mL

solubility

-

solubility

-

solubility

DMSO: ≥30 mg/mL

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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