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F8315

Fucoidan from Undaria pinnatifida

≥95%

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500 mg
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$345.00

About This Item

CAS Number:
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352201

$345.00


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biological source

algae (Undaria pinnatifida)

Quality Level

assay

≥95%

form

powder

color

white to off-white

useful pH range

3.0 -7.0

solubility

water: 10 mg/mL, colorless to faintly yellow

storage temp.

room temp

General description

Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.
Fucoidan has a complex chemical composition. It contains mannose, galactose, glucose, xylose and other monosaccharides. It is also composed of uronic acids, acetyl groups and protein.

Application

Fucoidan from Undaria pinnatifida has been used to assess its antimicrobial potential in vitro.[1]

Biochem/physiol Actions

Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation which subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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This Item
F8065F8190F5631
biological source

algae (Undaria pinnatifida)

biological source

algae (Macrocystis pyrifera)

biological source

algae (Fucus Vesiculosus)

biological source

algae (Fucus Vesiculosus)

assay

≥95%

assay

≥85%

assay

≥95%

assay

-

solubility

water: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

water: 10 mg/mL, clear to hazy, colorless to very faintly brown

solubility

water: 10 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 10 mg/mL, clear to hazy, faintly yellow to brownish-yellow

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

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Fucoidan: structure and bioactivity
Li B, et al.
Molecules (Basel), 13(8), 1671-1695 (2008)
Arumugam Ponnan et al.
Environmental science and pollution research international, 27(25), 31760-31766 (2020-06-07)
Fucoidan is a unique bioactive and dietary polymer enriched mainly in the cell wall matrix of the brown seaweeds. This present study was intended to reveal the antigenotoxicity effect of fucoidan on 4-nitroquinolin-1-oxide (4-NQO) induced genetics damage and apoptosis in
Xiang Li et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1661-1667 (2014-06-07)
Nuclear imaging of active plaques still remains challenging. Advanced atherosclerotic plaques have a strong expression of P-selectin by the endothelium overlying active atherosclerotic plaques, but not on the endothelium overlying inactive fibrous plaques. We proposed a new approach for noninvasive



Global Trade Item Number

SKUGTIN
F8315-500MG04061833620496

Questions

1–3 of 3 Questions  
  1. Does it have a reference of molecular weight, total sugar content, and sulfate content for each plot? I'll take experiments on it and would like to get into it. Thank you.

    1 answer
    1. For this product, the total carbohydrate content is typically around 60 percent by weight. Unfortunately, neither the molecular weight nor the sulfate content is tested.

      Helpful?

  2. What is the monosaccharide composition of this fucoidan? How much is fucose relative to glucuronic acid, mannose, galactose and xylose?

    1 answer
    1. This product has not been tested to determine the monosaccharide profile. In general, publications suggest that Fucoidan from Undaria pinnatifida is made up of primarily fucose and galactose. Please see the link below to review a publication that may be of interest:
      https://pmc.ncbi.nlm.nih.gov/articles/PMC6164441/#:~:text=pinnatifida%2Dderived%20fucoidan%20are%20fucose,and%20sulfate%20are%20also%20present.

      Helpful?

  3. Could you please share a reference to the extraction and purification method used for this sample? I have it as a standard in my exxperiment and would like to get insights into it. Thank you

    1 answer
    1. The extraction and purification methods for this product are considered proprietary information.

      Helpful?

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