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G2879

Glycine hydrochloride

≥99% (HPLC), NMDA receptors regulator, powder

Synonym(s):

Aminoacetic acid hydrochloride, Glycine HCl, Glycocoll hydrochloride, Aminoacetic acid, Aminoethanoic acid, Glycocoll

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Size/SKUAvailabilityPrice
100 g

Available to ship TODAY

$413.00
500 g

Available to ship TODAY

$241.00
1 kg

Available to ship TODAYfromMILWAUKEE

$413.00

About This Item

Linear Formula:
H2NCH2CO2H · HCl
CAS Number:
Molecular Weight:
111.53
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32
EC Number:
227-841-8
MDL number:

$413.00


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Product Name

Glycine hydrochloride, ≥99% (HPLC)

Quality Segment

assay

≥99% (HPLC)

form

powder

mol wt

111.53

storage condition

(Tightly closed Dry)

concentration

≤100%

technique(s)

immunohistochemistry: suitable

mp

176-180 °C (lit.)

solubility

water: 0.5 g/mL, clear, colorless

storage temp.

room temp

SMILES string

Cl.NCC(O)=O

InChI

1S/C2H5NO2.ClH/c3-1-2(4)5;/h1,3H2,(H,4,5);1H

InChI key

IVLXQGJVBGMLRR-UHFFFAOYSA-N

General description

Research area: Neuroscience

Application

Glycine hydrochloride has been used as a component of Ag (silver)-stripping buffer for multiplex immunohistochemistry in mice tissues.
Glycine hydrochloride has been used:
  • in the preparation of glycine-HCl buffer
  • to elute serum immunoglobulins (IgGs) from the beads in order to check for the complete enrichment of core- and site-specific antibodies
  • to regenerate the sensor to elute the bound C-reactive protein (CRP)

Biochem/physiol Actions

Glycine comprises a single carbon molecule, that is attached to the amino and a carboxyl group. Glycine hydrochloride (Gly·HCl) is capable of liquifying native chitosan and also helps in the preparation of regenerated chitosan membrane. It can serve as an osmoprotectant. Glycine can act as a flexible link in proteins and can also allow the formation of helices. Free glycine may have a protecting role in tissues against ischemia, hypoxia, and reperfusion.Glycine has been studied as a potential treatment for sepsis, arthritis, adult respiratory distress syndrome, and other inflammatory diseases.
Glycine acts on receptors which bring out an enhanced chloride conductance. It shows highest concentrations in the spinal cord as compared to elsewhere in the brain. However, it interacts with and allostericaly activates the excitatory receptor N-methyl-D-aspartate (NMDA), thus, resulting in excitatory transmission in brain.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

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This Item
1372755005894119
description

≥99% (HPLC)

description

EMPROVE® EVOLVE

description

tested according to Ph. Eur.

description

analytical standard, for nitrogen determination according to Kjeldahl method

technique(s)

immunohistochemistry: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

gas chromatography (GC): suitable, titration: suitable, HPLC: suitable

assay

≥99% (HPLC)

assay

-

assay

100.0%

assay

≥99.0%

Quality Level

300

Quality Level

400

Quality Level

200

Quality Level

100

form

powder

form

powder

form

crystalline

form

-

storage temp.

room temp

storage temp.

2-30°C

storage temp.

-

storage temp.

-

mol wt

111.53

mol wt

-

mol wt

-

mol wt

-


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Pictograms

Corrosion

Signal Word

Danger

Hazard Codes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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