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Merck

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G2879

Glycine hydrochloride

≥99% (HPLC), NMDA receptors regulator, powder

Sinônimo(s):

Aminoacetic acid hydrochloride, Glycine HCl, Glycocoll hydrochloride, Aminoacetic acid, Aminoethanoic acid, Glycocoll

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Para você/SKUDisponibilidadePreço
100 g
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R$ 530,00
500 g
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R$ 1.775,00
1 kg
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R$ 3.055,00

Sobre este item

Fórmula linear:
H2NCH2CO2H · HCl
Número CAS:
Peso molecular:
111.53
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32
EC Number:
227-841-8
MDL number:

R$ 530,00


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Nome do produto

Glycine hydrochloride, ≥99% (HPLC)

Quality Segment

assay

≥99% (HPLC)

form

powder

mol wt

111.53

storage condition

(Tightly closed Dry)

concentration

≤100%

technique(s)

immunohistochemistry: suitable

mp

176-180 °C (lit.)

solubility

water: 0.5 g/mL, clear, colorless

storage temp.

room temp

SMILES string

Cl.NCC(O)=O

InChI

1S/C2H5NO2.ClH/c3-1-2(4)5;/h1,3H2,(H,4,5);1H

InChI key

IVLXQGJVBGMLRR-UHFFFAOYSA-N

General description

Research area: Neuroscience

Application

Glycine hydrochloride has been used as a component of Ag (silver)-stripping buffer for multiplex immunohistochemistry in mice tissues.
Glycine hydrochloride has been used:
  • in the preparation of glycine-HCl buffer
  • to elute serum immunoglobulins (IgGs) from the beads in order to check for the complete enrichment of core- and site-specific antibodies
  • to regenerate the sensor to elute the bound C-reactive protein (CRP)

Biochem/physiol Actions

Glycine comprises a single carbon molecule, that is attached to the amino and a carboxyl group. Glycine hydrochloride (Gly·HCl) is capable of liquifying native chitosan and also helps in the preparation of regenerated chitosan membrane. It can serve as an osmoprotectant. Glycine can act as a flexible link in proteins and can also allow the formation of helices. Free glycine may have a protecting role in tissues against ischemia, hypoxia, and reperfusion.Glycine has been studied as a potential treatment for sepsis, arthritis, adult respiratory distress syndrome, and other inflammatory diseases.
Glycine acts on receptors which bring out an enhanced chloride conductance. It shows highest concentrations in the spinal cord as compared to elsewhere in the brain. However, it interacts with and allostericaly activates the excitatory receptor N-methyl-D-aspartate (NMDA), thus, resulting in excitatory transmission in brain.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

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Este Item
33226G712615527
Glicina puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance)

Sigma-Aldrich

33226

Glicina

Glicina ReagentPlus®, ≥99% (HPLC)

Sigma-Aldrich

G7126

Glicina

Glicina meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

Sigma-Aldrich

15527

Glicina

description

≥99% (HPLC)

description

puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance)

description

ReagentPlus®, ≥99% (HPLC)

description

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

assay

≥99% (HPLC)

assay

99.7-101% (calc. to the dried substance)

assay

≥99% (HPLC)

assay

99-101% (based on anhydrous substance)

technique(s)

immunohistochemistry: suitable

technique(s)

IR spectroscopy: suitable

technique(s)

western blot: suitable

technique(s)

IR spectroscopy: suitable

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

crystalline powder

form

powder

form

crystalline powder

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

-

mol wt

111.53

mol wt

-

mol wt

-

mol wt

-


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1

Classe de armazenamento

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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