G8903
Ghrelin rat
lyophilized powder
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| Size/SKU | Availability | Price |
|---|---|---|
0.1 mg | Available to ship TODAYfromMILWAUKEE | $770.00 $654.50 |
About This Item
$654.50
List Price$770.00Save 15%Web-Only Promotion
Available to ship TODAYDetails
form
lyophilized powder
Quality Segment
color
white
solubility
1% acetic acid: 1 mg/mL, water: 1 mg/mL
UniProt accession no.
storage temp.
−20°C
Gene Information
rat ... Ghrl(59301)
General description
Ghrelin is a gut-brain orexigenic peptide that functions in hunger signaling. This peptide is prominently synthesized by stomach and transported to brain. However, a specific subset of hypothalamic neurons also produces this peptide. It is expressed in gastrointestinal tract, hypothalamic arcuate nucleus, pituitary, kidney, liver, heart, lung and adipose tissue This peptide is composed of 28 amino acids, and its Ser3 residue is N-octanoylated.
Application
Ghrelin rat has been used for intraperitoneal injections, and microinjections in rats to study its effects on celiac disease, and passive avoidance learning (PAV) and spatial learning, respectively. It has also been used for intracerebroventricular injection in rats to study its influence on penicillin-induced epileptiform activity in rat.
Biochem/physiol Actions
Ghrelin acts as a ligand for G-protein coupled receptor, GHS-R1A (growth hormone secretagogue receptor), and controls energy utilization and feeding. This peptide is involved in enhancing the value of rewarding foods, drugs and alcohol. In rats with diabetes, the expression of ghrelin increased as a result of cachexia. In rats with ovariectomy, the expression of this peptide decreased in the endometrium. This peptide controls cognitive functions and has neuroprotective roles in neurodegenerative disorders. In cultured cortical neuronal networks, ghrelin increases the rate of synapse formation and activity development.
Endogenous ligand to the orphan growth-hormone secretagogue receptor that stimulates the release of growth hormone from the pituitary.
Physical form
Lyophilized from 0.1% aqueous TFA
Other Notes
Lyophilized from 0.1% TFA in H2O
1 of 1
This Item | |||
|---|---|---|---|
| description lyophilized powder | description lyophilized powder, essentially globulin free, ≥99% (agarose gel electrophoresis) | description - | description This Human Ghrelin (active) ELISA is used to measure & quantify Ghrelin (active) levels in Metabolism & Endocrine & Neuroscience research. |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| form lyophilized powder | form lyophilized powder | form powder | form - |
| Gene Information rat ... Ghrl(59301) | Gene Information rat ... ALB(24186) | Gene Information - | Gene Information - |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| UniProt accession no. | UniProt accession no. | UniProt accession no. - | UniProt accession no. |
| color white | color - | color beige | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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