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G9003

D-Glutamine

≥98% (HPLC)

Synonym(s):

D-2-Aminoglutaramic acid, D-Glutamic acid 5-amide

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About This Item

Empirical Formula (Hill Notation):
C5H10N2O3
CAS Number:
Molecular Weight:
146.14
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
1723796
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Product Name

D-Glutamine, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white

application(s)

cell analysis

SMILES string

N[C@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1

InChI key

ZDXPYRJPNDTMRX-GSVOUGTGSA-N

General description

Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids.

Application

D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer.

Biochem/physiol Actions

Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%.

Other Notes

Unnatural isomer of glutamine

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G1149G1001PHL83798
description

≥98% (HPLC)

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BioReagent, suitable for insect cell culture, ≥99% (HPLC)

description

≥99% (TLC)

description

phyproof® Reference Substance

form

powder

form

powder

form

powder

form

crystals

assay

≥98% (HPLC)

assay

≥99% (HPLC)

assay

≥99% (TLC)

assay

≥98.0% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

-

color

white

color

white

color

white to off-white

color

-

application(s)

cell analysis

application(s)

-

application(s)

-

application(s)

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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