H139
HA-1077 dihydrochloride
solid, ≥98% (HPLC)
Synonym(s):
1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride, Fasudil dihydrochloride
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAY | $460.00 |
10 mg | Available to ship TODAY | $721.00 |
About This Item
$460.00
Available to ship TODAYDetails
Quality Segment
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
color
white to off-white
solubility
H2O: >10 mg/mL
SMILES string
Cl[H].Cl[H].O=S(=O)(N1CCCNCC1)c2cccc3cnccc23
InChI
1S/C14H17N3O2S.2ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;;/h1,3-5,7,11,15H,2,6,8-10H2;2*1H
InChI key
NOXXIYDYFSNHDF-UHFFFAOYSA-N
Application
- to relax cantilevers
- in the functional assessment of isolated coronary arteries
- to investigate the effect of azaindole-1, fasudil on acute hypoxic pulmonary vasoconstriction (HPV)
Biochem/physiol Actions
1 of 1
This Item | ||
|---|---|---|
| description solid, ≥98% (HPLC) | description The Rho kinase inhibitor, CAS 872543-07-6, is a cell-permeable, highly specific, reversible, potent, and ATP-competitive inhibitor of Rho-associated kinase (ROCK; Ki = 1.6 nM). | description - |
| form solid | form solid | form solid |
| assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level - |
| solubility H2O: >10 mg/mL | solubility water: 5 mg/mL, methanol: 5 mg/mL | solubility - |
| storage condition desiccated | storage condition desiccated (hygroscopic), protect from light, OK to freeze | storage condition - |
| color white to off-white | color white | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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