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H9250

Histone from calf thymus

Type II-A, lyophilized powder

Synonym(s):

histone type VIII-S

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Size/SKUAvailabilityPrice
100 mg

Available to ship TODAYfromMILWAUKEE

$111.00
500 mg

Available to ship TODAYfromMILWAUKEE

$466.00

About This Item

CAS Number:
UNSPSC Code:
41106305
NACRES:
NA.51
Beilstein/REAXYS Number:
1895465
MDL number:
Form:
lyophilized powder
Biological source:
bovine (calf) thymus

$111.00


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biological source

bovine (calf) thymus

Quality Segment

type

Type II-A

form

lyophilized powder

application(s)

cell analysis

storage temp.

2-8°C

General description

Histones are octameric proteins containing H3, H4, H2A and H2B. It is the core protein around which DNA is wound forming the nucleosome structure. The core histone proteins contain globular domains. Each protein is composed of basic amino acids at its N-terminal. The H2A has an extra amino acid at its C-terminal end forming a histone tail. The nucleosome structure is stabilized by the linker histones during chromatin condensation.

Application

Histone from calf thymus has been used:
  • in methyltransferase reaction mixture for methyltransferase assay
  • in in vitro binding assay, to explore the potential binding of the MORF4 (mortality factor on chromosome 4) - related gene on chromosome 15 (MRG15) chromo domain with histone
  • in in vitro coculture assays, to stimulate liver resident Kupffer cells

Biochem/physiol Actions

The core histones are involved in histone-histone interactions and maintains the organization of the nucleosomal DNA. The histone tail helps in forming higher-order nucleosomal structures. The overall structure and action of chromatin fiber is regulated by histone modifications.

Features and Benefits

Do not confuse Sigma "Type" designations with the "Fraction" designations used by Luck and co-workers.

Preparation Note

Unfractionated whole histone

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This Item
H5505H438014155
description

Type II-A, lyophilized powder

description

Type III-S

description

Type VIII-S

description

Purified bovine Histone H1 protein for use as a substrate in histone modification assays (HAT, HDAC, DNMT) and chromatin assembly studies.

biological source

bovine (calf) thymus

biological source

bovine (calf) thymus

biological source

bovine (calf) thymus

biological source

bovine

form

lyophilized powder

form

powder

form

powder

form

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

type

Type II-A

type

Type III-S

type

Type VIII-S

type

-

application(s)

cell analysis

application(s)

-

application(s)

-

application(s)

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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