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I2764

ML-7

≥98% (TLC), myosin light chain kinase inhibitor, powder

Synonym(s):

1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride

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Size/SKUAvailabilityPrice
5 mg
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$186.00

About This Item

Empirical Formula (Hill Notation):
C15H17IN2O2S · HCl
CAS Number:
Molecular Weight:
452.74
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (TLC)
Form:
powder

$186.00


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Product Name

ML-7, powder

assay

≥98% (TLC)

Quality Segment

form

powder

color

white

solubility

ethanol: water (1:1): 10 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cl.Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3

InChI

1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H

InChI key

KDDALCDYHZIZMH-UHFFFAOYSA-N

Gene Information

Application

ML-7 has been used as a myosin light chain kinase (MLCK) inhibitor in various experiments.

Biochem/physiol Actions

Selective myosin light chain kinase inhibitor.

Features and Benefits

This compound is featured on the Ca/CaMKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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1 of 1

This Item
CB_88113007EHU222191475880
vibrant-m

ML-1

description

powder

description

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA, 88113007, human blood, Lymphoblastoid

description

targeting human MYLK (2)

description

A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM).

assay

≥98% (TLC)

assay

-

assay

-

assay

>98% (TLC)

form

powder

form

-

form

lyophilized powder

form

solid

Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−196°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

ethanol: water (1:1): 10 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

-

solubility

DMSO: 4.5 mg/mL, 50% ethanol: 4.5 mg/mL

color

white

color

-

color

-

color

white


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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