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I3266

Anti-Human IgG (Fab specific), F(ab′)2 fragment antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

F(ab′)₂ IgG

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1 mL
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$483.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162431
Conjugate:
unconjugated
Clone:
polyclonal
Application:
QPA
Citations:
4

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biological source

goat

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

quantitative precipitin assay: 2.0 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Immunoglobulins (Igs) belongs to immunoglobulin super-family (IgSF). Igs in general, consist of two heavy (H) chains and two light (L) chains. The L chain can be either κ or a λ chain. Each chain contains one NH2-terminal “variable" (V) region and one or more COOH-terminal “constant” (C) regions. Each of which consists of two sandwiched β pleated sheets ′pinned′ together by a disulfide bridge. There are five main classes of Igs based on heavy chain C domains, they are, IgM, IgG, IgA, IgD, and IgE isotypes. IgG can be divided into four subclasses, IgG1, IgG2, IgG3, and IgG4. Each subclass possesses distinct biologic properties.

Application

Anti-Human IgG (Fab specific), F(ab′)2 fragment antibody produced in goat has been used in enzyme linked immunosorbent assay (ELISA) and biosensor methodology.

Biochem/physiol Actions

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) is digested by papain and yields two Fab fragments, each of which can bind antigen, and a single Fc fragment. IgG is split by pepsin splits into an Fc fragment and a single dimeric F(ab)2 that can cross-link as well as bind antigens.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 0.05% sodium azide as preservative

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Human IgG (Fab specific), F(ab′)2 fragment antibody produced in goat affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

I3266

Anti-Human IgG (Fab specific), F(ab′)2 fragment antibody produced in goat

Anti-Mouse IgG (Fab specific) F(ab′)2 fragment antibody produced in goat affinity isolated antibody

Sigma-Aldrich

M0659

Anti-Mouse IgG (Fab specific) F(ab′)2 fragment antibody produced in goat

Anti-Mouse IgG (Fab specific) F(ab′)2 fragment–FITC antibody produced in goat affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

F8521

Anti-Mouse IgG (Fab specific) F(ab′)2 fragment–FITC antibody produced in goat

Anti-Mouse IgG (Fab specific) F(ab′)2 fragment–FITC antibody produced in goat affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

F2653

Anti-Mouse IgG (Fab specific) F(ab′)2 fragment–FITC antibody produced in goat

description

affinity isolated antibody, buffered aqueous solution

description

affinity isolated antibody

description

affinity isolated antibody, buffered aqueous solution

description

affinity isolated antibody, buffered aqueous solution

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

biological source

goat

biological source

goat

biological source

goat

biological source

goat

technique(s)

quantitative precipitin assay: 2.0 mg/mL

technique(s)

indirect ELISA: suitable

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:320

technique(s)

flow cytometry: 1:100, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:160

conjugate

unconjugated

conjugate

unconjugated

conjugate

FITC conjugate

conjugate

FITC conjugate

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

shipped in

dry ice

shipped in

dry ice

shipped in

-

shipped in

-

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Storage Class

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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