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I3391

Anti-Human IgG (Fc specific), F(ab′)2 fragment antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Goat anti-human IgG

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1 mL

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$444.00
$377.40

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162436
Conjugate:
unconjugated
Clone:
polyclonal
Application:
—
Citations:
11

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biological source

goat

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

concentration

2.0 mg/mL protein

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

IgG antibody plays a crucial role in humoral immune responses such as phagocytosis, complement activation, placental transport and cell surface-receptor binding. Anti-human IgG (Fc specific), F(ab′)2 fragment antibody can be used as a capture antibody in antibody-binding assay for soluble ICAM-1-Fc. Goat anti-human-IgG (Fc specific) F(ab′)2 antibody reacts specifically with human IgG but does not react with other immunoglobulins.
IgG is the main type of antibody in human serum, secreted by the B cells. It consists of four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, which are linked by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4.

Immunogen

Purified human IgG

Application

Anti-human IgG (Fc specific), F(ab′)2 fragment antibody can be used in ELISA to determine human IgG1-Fc protein.
Anti-Human IgG (Fc specific), F(ab′)2 fragment antibody produced in goat has been used in studying the antibody binding assay of soluble intercellular adhesion molecule-1 (ICAM-1)-Fc.

Biochem/physiol Actions

IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 0.05% sodium azide

Preparation Note

Adsorbed to reduce background with mouse or rat samples.
Useful when trying to avoid background staining due to the presence of Fc receptors.

Other Notes

Antibody adsorbed with mouse and rat IgG

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Human IgG (Fc specific), F(ab′)2 fragment antibody produced in goat affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

I3391

Anti-Human IgG (Fc specific), F(ab′)2 fragment antibody produced in goat

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment−Peroxidase antibody produced in goat affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

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Anti-Human IgG (γ-chain specific), F(ab′)2 fragment−Peroxidase antibody produced in goat

Anti-Mouse IgG (Fc specific) F(ab′)2 fragment antibody produced in goat 2.0 mg/mL, affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

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Anti-Mouse IgG (Fc specific) F(ab′)2 fragment antibody produced in goat

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment−Alkaline Phosphatase antibody produced in goat affinity isolated antibody, buffered aqueous glycerol solution

Sigma-Aldrich

A3312

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment−Alkaline Phosphatase antibody produced in goat

description

affinity isolated antibody, buffered aqueous solution

description

affinity isolated antibody, buffered aqueous solution

description

2.0 mg/mL, affinity isolated antibody, buffered aqueous solution

description

affinity isolated antibody, buffered aqueous glycerol solution

biological source

goat

biological source

goat

biological source

goat

biological source

goat

conjugate

unconjugated

conjugate

peroxidase conjugate

conjugate

unconjugated

conjugate

alkaline phosphatase conjugate

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous glycerol solution

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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