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I3642

Monoclonal Anti-Interleukin-1β antibody produced in mouse

clone 8516.311, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-IL-1β

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Size/SKUAvailabilityPrice
0.5 mg

Available to ship TODAYfromMILWAUKEE

$1,090.00

About This Item

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
8516.311, monoclonal
Application:
FACS, IHC, Neutral, WB
Citations:
7

$1,090.00


Available to ship TODAYDetails


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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

8516.311, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

flow cytometry: suitable, immunohistochemistry: 8-25 μg/mL using human PBMC′s, neutralization: suitable, western blot: 1 μg/mL

isotype

IgG1

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL1B(3553)

Immunogen

purifed, E. coli-derived, recombinant human IL-1β.

Application

May used in immunoblotting, immunohistochemistry, ELISA, and neutralization assays

Biochem/physiol Actions

The antibody will neutralize the biological activity of recombinant human IL-1β. It will not neutralize the activity of recombinant human IL-α, recombinant mouse IL-1α, or recombinant mouse IL-1β. When immobilized on a microplate, this antibody will capture both recombinant as well as natural human IL-1β. In immunoblotting, the antibody shows ~25% cross-reactivity with recombinant rat IL-1β and <5% cross-reactivity with recombinant mouse IL-1β and recombinant porcine IL-1β. Additionally, in immunoblotting, the antibody exhibits no cross-reactivity with recombinant mouse IL-α, recombinant human IL-1ra, recombinant mouse IL-1ra, or recombinant rat IL-1α.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Preparation Note

Monoclonal Anti-Interleukin-1(IL-1) (mouse IgG1 isotype) is purified from a mouse hybridoma utilizing Protein A affinity chromatography.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
I3767SAB1406017AV54324
description

clone 8516.311, purified immunoglobulin, lyophilized powder

description

IgG fraction of antiserum

description

purified immunoglobulin, buffered aqueous solution

description

affinity isolated antibody

clone

8516.311, monoclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

Gene Information

human ... IL1B(3553)

Gene Information

mouse ... Il1b(16176)

Gene Information

human ... IL1B(3553)

Gene Information

human ... IL1B(3553)

biological source

mouse

biological source

goat

biological source

mouse

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

species reactivity

human

species reactivity

mouse

species reactivity

human

species reactivity

human

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody


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Storage Class

13 - Non Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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