The stock solutions may be stored at -20 degrees C in aliquots. Long-term stability studies have not been performed. However, information found in published literature indicates that it is quite stable. Please see the link below to review one example.
https://pubmed.ncbi.nlm.nih.gov/18933/
I6504
(−)-Isoproterenol hydrochloride
≥98% (TLC), powder, β-adrenoceptor agonist
Synonym(s):
(−)-Isoprenaline hydrochloride, (−)-N-Isopropyl-L-noradrenaline hydrochloride, (R)-3,4-Dihydroxy-α-(isopropylaminomethyl)benzyl alcohol hydrochloride
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| Size/SKU | Availability | Price |
|---|---|---|
100 mg | Estimated to ship onNovember 30, 2026fromMILWAUKEE | $38.20 |
500 mg | Available to ship TODAYfromMILWAUKEE | $98.50 |
1 g | Available to ship TODAYfromMILWAUKEE | $174.00 |
About This Item
Linear Formula:
3,4-(HO)2C6H3CH(OH)CH2NHCH(CH3)2·HCl
CAS Number:
Molecular Weight:
247.72
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
6077193
Product Name
(−)-Isoproterenol hydrochloride,
Quality Segment
mp
175 °C (dec.) (lit.)
solubility
soluble (50 mg/ml: H2O)
storage temp.
−20°C
SMILES string
Cl[H].CC(C)NC[C@H](O)c1ccc(O)c(O)c1
InChI
1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H/t11-;/m0./s1
InChI key
IROWCYIEJAOFOW-MERQFXBCSA-N
Gene Information
human ... ADRB2(154)
Application
Biochem/physiol Actions
Isoproterenol hydrochloride is useful in post transplantal organ recovery. It exhibits ionotropic and chronotropic effects. With respect to donor heart recovery, isoproterenol hydrochloride decreases peripheral and systemic vascular resistance. Isoproterenol also increases the heart rate.
β-adrenoceptor agonist; increases cytosolic cAMP.
Preparation Note
This material can be dissolved in 50 mg/ml of H2O.
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This Item | |||
|---|---|---|---|
| description - | description - | description powder | description Pharmaceutical Secondary Standard; Certified Reference Material |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 300 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. - | storage temp. 2-30°C |
| solubility soluble (50 mg/ml: H2O) | solubility - | solubility - | solubility - |
| Gene Information human ... ADRB2(154) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) | Gene Information - |
| mp 175 °C (dec.) (lit.) | mp 215 °C (dec.) (lit.) | mp 143-145 °C (lit.) | mp 165-175 °C (dec.) (lit.) |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
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is product I65is product I6504 stable if reconstituted, aliquoted, and then frozen at -20C?
1 answer-
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Wie man das Produkt Isoproterenol-hydrochlorid #I6504 am besten? Und gibt es eine Konzentrationsangabe, bei der es sich am besten löst?
1 answer-
To order this material, please navigate to the link https://www.sigmaaldrich.com/support/customer-support, click on "Pricing & Availability" under the Products Section with all the required information so that a member of the Customer Service team can reach out to assist further.
This material can be dissolved in 50 mg/ml of H2O.
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How should (-)-Isoproterenol hydrochloride, Product I6504, be stored?
1 answer-
(-)-Isoproterenol hydrochloride is a powder that needs to be stored at -20°C.
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What can be used to make a solution of (-)-Isoproterenol hydrochloride, Product I6504?
1 answer-
We test the solubility of (-)-Isoproterenol hydrochloride in water at a concentration of 50 mg/mL. Isoproterenol hydrochloride is also soluble in ethanol at 20 mg/mL.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Can I use a brownish-pink solution of (-)-Isoproterenol hydrochloride, Product I6504?
1 answer-
Aqueous solutions become pink to brownish-pink when exposed to air, and almost immediately so when made alkaline. This color change indicates degradation.
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