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Monoclonal Anti-Interleukin-2 antibody produced in mouse

Name: Monoclonal Anti-Interleukin-2 antibody produced in mouse
Brand: SIGMA
Price: 1170 USD
Availability: InStock

clone 5334, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-IL2, Anti-Lymphokine, Anti-TCGF

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Size/SKU	Availability	Price
500 μg	Check Cart for Availability	$1,170.00

About This Item

NACRES:

NA.41

UNSPSC Code:

51111800

Conjugate:

unconjugated

Clone:

5334, monoclonal

Application:

FACS, IHC, Neutral

Citations:

$1,170.00

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Properties

biological source

mouse

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

5334, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

flow cytometry: 25 μg/mL, immunohistochemistry: 8-25 μg/mL, neutralization: suitable

isotype

IgG1

UniProt accession no.

P60568

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL2(3558)

Description

General description

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4⁺ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle
Monoclonal Anti-Interleukin-2 recognizes human Interleukin-2. It does not react with mouse IL-2.

Immunogen

purified, E. coli-derived recombinant human interleukin-2.

Application

Anti-interleukin-2 antibody may be used in immunohistochemistry at a working concentration of 8-25 μg/ml in human peripheral blood leukocytes. For flow cytometry a concentration of 25 μg/ml may be used. The antibody is suitable for IL-2 neutralization assays.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	I8273	I7401	SAB1403970
Sigma-Aldrich I6784 Monoclonal Anti-Interleukin-2 antibody produced in mouse	$Anti-Interleukin-2 antibody produced in goat IgG fraction of antiserum, lyophilized powder$ Sigma-Aldrich I8273 Anti-Interleukin-2 antibody produced in goat	Sigma-Aldrich I7401 Anti-Interleukin-2 antibody produced in goat	Sigma-Aldrich SAB1403970 Monoclonal Anti-IL2, (C-terminal) antibody produced in mouse
description clone 5334, purified immunoglobulin, lyophilized powder	description IgG fraction of antiserum, lyophilized powder	description affinity isolated antibody, lyophilized powder	description clone 1C5, purified immunoglobulin, buffered aqueous solution
species reactivity human	species reactivity human	species reactivity human	species reactivity human
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source mouse	biological source goat	biological source goat	biological source mouse
clone 5334, monoclonal	clone polyclonal	clone polyclonal	clone 1C5, monoclonal
Gene Information human ... IL2(3558)	Gene Information human ... IL2(3558)	Gene Information human ... IL2(3558)	Gene Information human ... IL2(3558)
antibody form purified immunoglobulin	antibody form IgG fraction of antiserum	antibody form affinity isolated antibody	antibody form purified immunoglobulin

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Storage Class

13 - Non Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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