I8280
Indomethacin
meets USP testing specifications
Synonym(s):
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
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About This Item
Quality Segment
agency
USP/NF, meets USP testing specifications
assay
98.0-102.0%
form
powder
mode of action
enzyme | inhibits
SMILES string
COc1ccc2n(c(C)c(CC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3
InChI
1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
InChI key
CGIGDMFJXJATDK-UHFFFAOYSA-N
Gene Information
human ... ALB(213), ALOX5(240), ELA2(1991), GPR44(11251), IL1A(3552), PLA2G1B(5319), PTGDR(5729), PTGS1(5742), PTGS2(5743)
mouse ... Alox5(11689), Ptgdr(19214), Ptger1(19216), Ptger2(19217), Ptger3(19218), Ptger4(19219), Ptgs1(19224), Ptgs2(19225)
rat ... Alox5(25290), Ptgs1(24693), Ptgs2(29527)
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description meets USP testing specifications | description Pharmaceutical Secondary Standard; Certified Reference Material | description 98.0-102.0%, meets EP testing specifications | description European Pharmacopoeia (EP) Reference Standard |
| mode of action enzyme | inhibits | mode of action - | mode of action enzyme | inhibits | mode of action - |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level - |
| assay 98.0-102.0% | assay - | assay 98.0-102.0% (in accordance with EP) | assay - |
| form powder | form - | form powder or crystals | form - |
| Gene Information human ... ALB(213), ALOX5(240), ELA2(1991), GPR44(11251), IL1A(3552), PLA2G1B(5319), PTGDR(5729), PTGS1(5742), PTGS2(5743) | Gene Information human ... PTGS1(5742), PTGS2(5743) | Gene Information human ... ALB(213), ALOX5(240), ELA2(1991), GPR44(11251), IL1A(3552), PLA2G1B(5319), PTGDR(5729), PTGS1(5742), PTGS2(5743) | Gene Information human ... PTGS1(5742), PTGS2(5743) |
| agency USP/NF | agency traceable to USP 1341001, traceable to Ph. Eur. I0200000 | agency meets EP testing specifications | agency - |
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 1 Oral
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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