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I8635

Anti-Human IgG (whole molecule) antibody produced in rabbit

whole antiserum

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Ihnen/SKUVerfügbarkeitPreis
2 mL

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200,00 €
170,00 €

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162452
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), QPA
Citations:
5

170,00 €

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biological source

rabbit

Quality Segment

300

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

secondary antibodies

clone

polyclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:60,000, quantitative precipitin assay: 2.5 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobin has two heavy (H) and two light (L) chains, held together by disulphide linkages. Each light chain comprises of one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal regions. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.

Application

Anti-Human IgG (whole molecule) antibody produced in rabbit has been used in enzyme linked immunosorbent assay.

Biochem/physiol Actions

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
IgG1 deficiency results in hypogammaglobulinemia. IgG2 deficiency increases susceptibility to bacterial infections, IgG3 mediates effector functions and IgG4 is associated with asymptomatic infection. IgG antibodies have enormous therapeutic potential and the Fc region is for the development of therapeutic antibody.

Preparation Note

delipidized

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Sigma-Aldrich

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Anti-Kaninchen-IgG (Gesamtmolekül)

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

technique(s)

indirect ELISA: 1:60,000, quantitative precipitin assay: 2.5 mg/mL

technique(s)

indirect ELISA: 1:80,000, quantitative precipitin assay: 3.0-4.0 mg/mL

technique(s)

indirect ELISA: 1:40,000, quantitative precipitin assay: 4.0 mg/mL

technique(s)

indirect ELISA: 1:30,000, quantitative precipitin assay: 3.0-4.5 mg/mL

antibody form

whole antiserum

antibody form

IgG fraction of antiserum

antibody form

whole antiserum

antibody form

IgG fraction of antiserum

biological source

rabbit

biological source

rabbit

biological source

goat

biological source

goat

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

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Lagerklasse

10 - Combustible liquids

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WGK 3

flash_point_f

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flash_point_c

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