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I9404

Interleukin-10/Fc Chimera (non-lytic) human

>98% (SDS-PAGE), recombinant, expressed in NS.1 cells, buffered aqueous solution

Synonym(s):

IL-10:Fc (non-lytic) human

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Size/SKUAvailabilityPrice
10 μg
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$1,030.00

About This Item

UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
Form:
buffered aqueous solution
Assay:
>98% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in NS.1 cells
Mol wt:
98 kDa

$1,030.00


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biological source

human

Quality Segment

recombinant

expressed in NS.1 cells

assay

>98% (SDS-PAGE)

form

buffered aqueous solution

mol wt

98 kDa

packaging

pkg of 10 μg

impurities

endotoxin, tested

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL10(3586)

General description

The gene IL-10 (interleukin-10) is mapped to human chromosome 1q31-32.[1] It is secreted by monocytes and lymphocytes.[2]

Biochem/physiol Actions

IL-10 (interleukin-10) is an anti-inflammatory cytokine. High levels of IL-10 are present in late syphilis.[3] It suppresses Th1 (T helper) cytokines. IL-10 also controls the differentiation and proliferation of T cells, B cells, natural killer cells, antigen-presenting cells and mast cells.[1]
Possesses the biological function of the IL-10 moiety and a prolonged circulating half-life determined by the Fc domain.

Physical form

Solution in 0.2 μm filtered phosphate buffered saline, pH 7.4.

Other Notes

Dimeric fusion protein consisting of human IL-10 fused to mutant human IgG1 Fc.

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SRP3312H7541I9276
description

>98% (SDS-PAGE), recombinant, expressed in NS.1 cells, buffered aqueous solution

description

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

description

IL-10, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture

description

≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture

recombinant

expressed in NS.1 cells

recombinant

expressed in E. coli

recombinant

expressed in HEK 293 cells

recombinant

expressed in baculovirus infected Sf21 cells

biological source

human

biological source

human

biological source

human

biological source

human

assay

>98% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

mol wt

98 kDa

mol wt

18.6 kDa

mol wt

dimer 17 kDa (glycosylated)

mol wt

18 kDa

form

buffered aqueous solution

form

lyophilized

form

lyophilized powder

form

lyophilized powder

shipped in

wet ice

shipped in

wet ice

shipped in

-

shipped in

-


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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