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N6414

NN-DNJ

≥98% (HPLC)

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Size/SKUAvailabilityPrice
5 mg
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$261.00

About This Item

Empirical Formula (Hill Notation):
C15H31NO4
CAS Number:
Molecular Weight:
289.41
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$261.00


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Quality Segment

assay

≥98% (HPLC)

form

solid

solubility

DMSO: >10 mg/mL

storage temp.

−20°C

SMILES string

CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI

1S/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3/t12-,13+,14-,15-/m1/s1

InChI key

FTSCEGKYKXESFF-LXTVHRRPSA-N

Biochem/physiol Actions

NN-DNJ is a glucosidase inhibitor that acts as a pharmacologic chaperone.
NN-DNJ is a glucosidase inhibitor that acts as a pharmacologic chaperone. NN-DNJ also acts synergistically with proteostasis modulators such as celastrol and MG132 to stabilize mutant proteins in properly folded states. NN-DNJ stabilizes various proteins against misfolding, increasing proper trafficking from the endoplasmic reticulum. There is potential use in studying diseases marked by misfolded proteins and has shown antiviral activity.

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This Item
B8299D9305SML3666
description

≥98% (HPLC)

description

film (dried in situ)

description

-

description

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥97% (HPLC)

form

solid

form

film (dried in situ)

form

powder

form

powder

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

solubility

DMSO: >10 mg/mL

solubility

water: 9.80-10.20 mg/mL, clear, colorless

solubility

water: 19.60-20.40 mg/mL, clear, colorless

solubility

DMSO: 2 mg/mL, clear


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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