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N9528

Anti-Neuropeptide Y (NPY) antibody produced in rabbit

whole antiserum

Synonym(s):

NPY Antibody - Anti-Neuropeptide Y (NPY) antibody produced in rabbit, Npy Antibody

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Size/SKUAvailabilityPrice
25 μL

Available to ship TODAYfromMILWAUKEE

$208.00
0.2 mL

Available to ship TODAYfromMILWAUKEE

$902.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00162717
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i)
Citations:
70

$208.00

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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

rat, sheep, pig, human

packaging

antibody small pack of 25 μL

technique(s)

: suitable using suitable for IHC on rat brain perfused with 4% paraformaldehyde, indirect ELISA: 1:5,000-1:10,000 using using peptide coating at 0.5-1 μg/well in 0.05 M carbonate/bicarbonate buffer, pH 9.6, and pNPP as substrate

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Npy(24604)

General description

Anti-Neuropeptide Y (NPY) is developed in rabbits using synthetic neuropeptide Y (porcine) conjugated to keyhole limpet hemocyanin (KLH) as the immunogen.
Neuropeptide Y (NPY), a 36-amino acid peptide amide, is a major regulatory neuropeptide widely distributed in the mammalian central (CNS) and peripheral nervous systems (PNS). NPY belongs to the pancreatic polypeptide family of peptides which are characterized by a common tertiary structure. Within this family, an intestinal peptide hormone, peptide YY (PYY), is most closely related to NPY. In the CNS, NPY is involved in regulation of blood pressure, memory processing, circadian rhythm, and stimulation of food intake. In the PNS, NPY has potent vasoconstrictor activity and acts as a neurotransmitter/neuromodulator of sympathetic neurons and adrenal glands. NPY is one of the most abundant peptides found in the CNS, widely distributed in the brain. High levels of NPY are present in the cerebral cortex, amygdaloid nuclei, hippocampal formation, and hypothalamus. In the PNS, NPY is found mainly in sympathetic neurons that innervate vascular smooth muscle, heart, and urogenital tract. The biological actions of NPY in the brain and periphery are mediated by at least two different NPY receptors, designated Y1 and Y2 receptor subtypes.

Immunogen

synthetic neuropeptide Y (NPY, porcine), conjugated to KLH. The corresponding sequence is highly conserved (single amino acid substitution) in human and rat NPY and is highly conserved (84% identity) in the C-terminus region (24-36) of human peptide YY.

Application

Anti-Neuropeptide Y (NPY) antibody produced in rabbit has been used in:
  • single-labeling immunocytochemistry
  • immunofluorescence
  • immunostaining
  • dot blot
  • radioimmunoassay (RIA)
  • enzyme-linked immunosorbent assay (ELISA)

Biochem/physiol Actions

Neuropeptide Y (NPY) plays a vital role in feeding behaviour, anxiety, epilepsy, circadian, rhythm memory processing, sleep, pain and drug addiction. In addition, it is also implicated in regulation of appetite, body weight and obesity. It controls central endocrine secretion and has potent vasoactive effects on the cardiovascular system. NPY is involved in the pathogenesis of atherosclerosis and coronary artery disease.
The antibody recognizes by ELISA, NPY (human), NPY (porcine), NPY (sheep), NPY (13-36), NPY (18-36), and may also cross-reacts with PYY (human). It does not cross-react with neurokinin B (NKB), neurokinin A (NKA), substance P (SP), calcitonin, somatostatin and BSA.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Neuropeptide Y (NPY) antibody produced in rabbit whole antiserum

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EZRMNPY

Rat/Mouse Neuropeptide Y (NPY) ELISA

description

whole antiserum

description

recombinant, expressed in HEK 293 cells

description

This Human Neuropeptide Y (NPY) ELISA is used to measure & quantify NPY levels in Metabolism & Neuroscience research.

description

This Rat/Mouse Neuropeptide Y (NPY) ELISA is used to measure & quantify NPY levels in Metabolism & Neuroscience research.

biological source

rabbit

biological source

rabbit

biological source

-

biological source

-

antibody form

whole antiserum

antibody form

purified antibody

antibody form

-

antibody form

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

-

clone

polyclonal

clone

2B5, recombinant monoclonal

clone

-

clone

-

Gene Information

rat ... Npy(24604)

Gene Information

human ... NPY(4852)

Gene Information

-

Gene Information

-

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Storage Class

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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