This product may be stored in room temperature. Concerning expiration, this product is assigned a product retest date. Products that, while considered stable, may be subject to degradation over time are assigned a periodic retest date to confirm quality. The lot specific retest date is reported on the Certificate of Analysis. Please see the link below to review a sample or lot specific Certificate:
https://www.sigmaaldrich.com/product/sigma/p7794#product-documentation
P7794
Penicillin G potassium salt
powder, suitable for cell culture, BioReagent
Synonym(s):
Benzylpenicillin potassium salt
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| Size/SKU | Availability | Price |
|---|---|---|
1000000 units | Check Cart for Availability | $25.60 |
10000000 units | Check Cart for Availability | $32.20 |
100000000 units | Check Cart for Availability | $164.00 |
About This Item
Empirical Formula (Hill Notation):
C16H17KN2O4S
CAS Number:
Molecular Weight:
372.48
PubChem Substance ID:
eCl@ss:
34010400
UNSPSC Code:
12352207
NACRES:
NA.76
EC Number:
204-038-0
MDL number:
Beilstein/REAXYS Number:
3832841
$25.60
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Product Name
Penicillin G potassium salt, powder, BioReagent, suitable for cell culture
product line
BioReagent
Quality Segment
form
powder
potency
1440-1680 units per mg
technique(s)
cell culture | mammalian: suitable
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
SMILES string
[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
InChI
1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
InChI key
IYNDLOXRXUOGIU-LQDWTQKMSA-M
General description
Chemical structure: β-lactam
Application
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Biochem/physiol Actions
Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.
Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.
Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Disclaimer
Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The potassium salt is soluble in H2O at 100 mg/mL.
1 of 1
This Item | |||
|---|---|---|---|
| description powder, BioReagent, suitable for cell culture | description 95.0 - 102.0% | description VETRANAL®, analytical standard | description Pharmaceutical Secondary Standard; Certified Reference Material |
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) gas chromatography (GC): suitable, HPLC: suitable | technique(s) - |
| antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum Gram-positive bacteria, Gram-negative bacteria | antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum - |
| mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes | mode of action - |
| product line BioReagent | product line - | product line VETRANAL® | product line - |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 300 |
| form powder | form powder | form - | form solid |
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Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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¿A qué temperatura debe de almacenarse este producto en polvo y por cuánto tiempo es estable?
1 answer-
Helpful?
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Is the reported potency for P7794 Penicillin G potassium salt based on the anhydrous/dried form, or is it based on an as-it-is basis? Also, what does the "S" signify in U/mgS for the reported potency results?
1 answer-
The potency test is reported on an "as is" basis. The "S" in U/mgS stands for unit per milligram solid.
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