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Q3638

Quetiapine hemifumarate salt

≥98% (HPLC), serotonin (5HT2) and dopamine (D2) receptor antagonist, powder

Synonym(s):

2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate, Quetiapine fumarate

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Size/SKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$102.00
50 mg

Available to ship TODAYfromMILWAUKEE

$434.00
$368.90

About This Item

Empirical Formula (Hill Notation):
C21H25N3O2S · 0.5C4H4O4
CAS Number:
Molecular Weight:
441.54
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$102.00


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Product Name

Quetiapine hemifumarate salt, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

DMSO: >10 mg/mL

originator

AstraZeneca

storage temp.

2-8°C

SMILES string

OC(=O)\C=C\C(O)=O.OCCOCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OCCOCCN5CCN(CC5)C6=Nc7ccccc7Sc8ccccc68

InChI

1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChI key

ZTHJULTYCAQOIJ-WXXKFALUSA-N

Gene Information

General description

Quetiapine is a derivative of dibenzothiazepine compound and is also referred to as seroquel and clemastine.

Application

Quetiapine hemifumarate salt has been used as an antagonist for β-arrestin 2 mutant T205M recruitment.

Biochem/physiol Actions

Quetiapine promotes oligodendrogenesis in vitro. It is used in treating depressive disorders.
Quetiapine hemifumarate is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.
Quetiapine hemifumarate is an atypical antipsychotic, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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This Item
1592704M149I9910
description

≥98% (HPLC)

description

United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 883.09 ((C21H25N3O2S)2 · C4H4O4)

description

≥98% (HPLC), solid

description

≥98% (HPLC)

form

powder

form

-

form

solid

form

solid

assay

≥98% (HPLC)

assay

-

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

room temp

storage condition

desiccated

storage condition

-

storage condition

desiccated

storage condition

-

solubility

DMSO: >10 mg/mL

solubility

-

solubility

H2O: 13 mg/mL

solubility

H2O: >20 mg/mL


Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - STOT SE 3

Storage Class

11 - Combustible Solids

Flash Point (°F)

No data available

Target Organs

Central nervous system

Flash Point (°C)

No data available



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