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RAB0147

Human DPPIV / CD26  ELISA Kit

for serum, plasma, cell culture supernatant and urine

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Pack SizeSKUAvailabilityPrice
1 kit
Please contact Customer Service for Availability
$850.00

About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... DPP4(1803)
Input:
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice

$850.00

Please contact Customer Service for Availability
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 25 pg/mL
standard curve range: 32.77-8000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... DPP4(1803)

General description

The Human CD26 (also known as DPPIV) ELISA (Enzyme- Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CD26 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human CD26

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Dipeptidyl peptidase 4 (DPPIV), also known as CD26 (cluster of differentiation 26), is localized on T- cell surface and interacts with adenosine deaminase (ADA), collagen and CD459. It plays a vital role in T cell co-stimulation, cell-to-cell adhesion, and in human immunodeficiency virus (HIV) infection.[1][2] Deletion of the DPPIV gene alters carbohydrate metabolism which in turn leads to mental retardation and hypotonia.[3] Abnormal expression of DPPIV is observed during liver regeneration, human cirrhosis and liver tumorigenesis.[2] DPPIV level is reduced in serum of chronic obstructive pulmonary disease (COPD) patients, hence, this protein has potential as a serologic marker for screening COPD.[4] DPP4 functions as a serine protease enzyme that catalyzes the cleavage of dipeptides from peptides containing proline or alanine residues. IL-13 induced DPPIV expression is upregulated in bronchial epithelial cells (BECs) and this expression might contribute to the development of asthmatic airway inflammation, cell proliferation and fibronectin (FN) production. This protein is a promising biomarker and therapeutic target for asthma.[5]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Gene Information

human ... DPP4(1803)

Gene Information

human ... FCER2(2208)

Gene Information

human ... CCL28(56477)

Gene Information

human ... CD40LG(959)

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine

input

sample type cell culture supernatant(s)
sample type serum
sample type urine
sample type plasma

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum
sample type urine

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 25 pg/mL
standard curve range: 32.77-8000 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4.5 pg/mL
standard curve range: 4.92-1200 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 25 pg/mL
standard curve range: 27.4-20000 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 8.23-6000 pg/mL

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

Kit Components Also Available Separately

Product No.
Description
SDS & Pricing
  • RABELADA
    ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
    SDS
  • RABELADB
    ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
    SDS
  • RABSTOP3
    ELISA Stop Solution (Item I)
    SDS
  • RABTMB3
    ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS
  • RABWASH4
    20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

10 - Combustible liquids

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
1129J0355
1122J0355
0922J0355
0510J0355
0503J0355

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Related Content

Taichi Shiobara et al.
Respiratory research, 17, 28-28 (2016-03-16)
Type 2 helper T-cell cytokines including IL-13 play a central role in the pathogenesis of bronchial asthma (BA). During the course of our research, our attention was drawn to dipeptidyl peptidase-4 (DPP4) as one of the molecules that were induced
Orazio Palumbo et al.
Molecular cytogenetics, 5(1), 1-1 (2012-01-05)
Chromosomal imbalances, recognized as the major cause of mental retardation, are often due to submicroscopic deletions or duplications not evidenced by conventional cytogenetic methods. To date, interstitial deletion of long arm of chromosome 2 have been reported for more than
Molecular analyses of human and rat dipeptidyl peptidase IV.
C A Abbott et al.
Advances in experimental medicine and biology, 421, 161-169 (1997-01-01)
View All Related Papers

Global Trade Item Number

SKUGTIN
RAB0147-1KT04061834960249