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S0191

Sonic Hedgehog Peptide from mouse

≥97% (SDS-PAGE), recombinant, expressed in E. coli, Fused to a histidine tag at the C-terminus, lyophilized powder

Synonym(s):

Shh

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25 μg

Available to ship TODAYfromMILWAUKEE

$453.00
$385.05

About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:

$385.05

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biological source

mouse

Quality Segment

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

0.4-3.0 μg/mL ED50

mol wt

predicted mol wt 20 kDa

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

<1 EU/μg

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Shh(20423)

General description

Sonic hedgehog (Shh) is a morphogenic glycoprotein. The gene encoding it is localized on mouse chromosome 5.

Application

Sonic hedgehog peptide from mouse has been used for neural differentiation.

Biochem/physiol Actions

Sonic hedgehog (Shh) has a role in fracture healing and regeneration. The protein associates with its receptor Patched (Ptc-1), de-represses Smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer.
Cell signaling peptide involved in embryonic morphogenic development of several tissues including Hensen′s node, the notochord, and the neural tube.
Involved in embryonic morphogenic development of several tissues including Hensen′s node, the notochord, and the neural tube.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4, containing 5% trehalose and 50 μg of bovine serum albumin per 1 μg of cytokine.

Other Notes

N-terminal peptide encoding amino acid residues 25-198.

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This Item
S9822S8321SRP3156
description

≥97% (SDS-PAGE), recombinant, expressed in E. coli, Fused to a histidine tag at the C-terminus, lyophilized powder

description

affinity isolated antibody, lyophilized powder

description

clone SH154, purified from hybridoma cell culture

description

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

biological source

mouse

biological source

goat

biological source

mouse

biological source

human

assay

≥97% (SDS-PAGE)

assay

-

assay

-

assay

≥98% (SDS-PAGE), ≥98% (HPLC)

recombinant

expressed in E. coli

recombinant

-

recombinant

-

recombinant

expressed in E. coli

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

-

form

lyophilized powder

form

lyophilized powder

form

buffered aqueous solution

form

lyophilized

Gene Information

mouse ... Shh(20423)

Gene Information

mouse ... Shh(20423)

Gene Information

human ... SHH(6469)
mouse ... Shh(20423)
rat ... Shh(29499)

Gene Information

human ... SHH(6469)


Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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