The GST tag is located at the N terminus of the protein. unable to share whether this protein contains a linker or not as this is considered proprietary.
S0439
SUMO-1 human
≥95% (SDS-PAGE), recombinant, expressed in E. coli (GST-tagged)
Synonym(s):
Sentrin-1
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| Size/SKU | Availability | Price |
|---|---|---|
500 μg | Check Cart for Availability | $473.00 |
About This Item
$473.00
Check Cart for Availability
recombinant
expressed in E. coli (GST-tagged)
Quality Segment
assay
≥95% (SDS-PAGE)
mol wt
38.5 kDa
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... SUMO1(7341)
General description
Small ubiquitin-like modifier 1 (SUMO-1), a protein, is one of the 5 SUMO paralogs expressed in mammalian cells with a low but significant homology with ubiquitin. This SUMO-1-GST fusion protein is produced from a DNA sequence corresponding to human SUMO-1 fused to a glutathione S-transferase (GST)-tag and is expressed in E. coli cells.
Application
Biochem/physiol Actions
Small ubiquitin-like modifier 1 (SUMO-1) plays a key role in modulating survival, migration, and signal transduction in some cell lines. It can prevent in vitro migration and invasion of RA fibroblast-like synoviocytes (FLSs). Higher expression of SUMO-1 may result in joint destruction in rheumatoid arthritis (RA).
Conjugated to a variety of proteins by UbcH9, including RanGAP1, IκBα, and PML without the requirement of an equivalent E3 ubiquitin ligase.
Physical form
Solution in 50 mM HEPES, pH 8.0, 150 mM NaCl and 1 mM DTT.
1 of 1
This Item | |||
|---|---|---|---|
| description ≥95% (SDS-PAGE), recombinant, expressed in E. coli (GST-tagged) | description His tagged recombinant protein, lyophilized powder | description clone 3D7, purified immunoglobulin, buffered aqueous solution | description Recombinant protein, aqueous solution, ≥25,000 units/mL |
| assay ≥95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) | assay - | assay ≥90% (SDS-PAGE) |
| recombinant expressed in E. coli (GST-tagged) | recombinant expressed in E. coli | recombinant - | recombinant expressed in E. coli |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| mol wt 38.5 kDa | mol wt 27 kDa | mol wt antigen ~38.6 kDa | mol wt 27 kDa |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. | UniProt accession no. - |
| Gene Information human ... SUMO1(7341) | Gene Information - | Gene Information human ... SUMO1(7341) | Gene Information - |
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Is S0439-1MG (SUMO-1 human) N- or C-terminal GST tagged? Is there any form of linker amino acids between the SUMO-1 sequence and the GST sequence?
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