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Monoclonal Anti-Superoxide Dismutase (SOD) antibody produced in mouse

Name: Monoclonal Anti-Superoxide Dismutase (SOD) antibody produced in mouse
Brand: SIGMA
Price: 482.8 USD
Availability: InStock

clone SD-G6, ascites fluid

Synonym(s):

Anti-ALS, Anti-ALS1, Anti-HEL-S-44, Anti-hSod1, Anti-IPOA, Anti-SOD, Anti-STAHP, Anti-homodimer

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Pack Size	SKU	Availability	Price
0.2 mL		Available to ship TODAYfromMILWAUKEE	$568.00 $482.80

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00164740

Conjugate:

unconjugated

Clone:

SD-G6, monoclonal

Application:

ELISA (i)

Citations:

$482.80

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

SD-G6, monoclonal

contains

15 mM sodium azide

species reactivity

canine, human, rat

technique(s)

indirect ELISA: 1:300

isotype

IgG1

UniProt accession no.

P00441

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SOD1(6647)
rat ... Sod1(24786)

Description

General description

Monoclonal Anti-Superoxide Dismutase (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Superoxide Dismutase (SOD) is a family of metalloenzymes widely distributed in both plants and animals. In mammalian tissues, three types of superoxide dismutase [Cu-Zn-SOD, Mn-SOD, extracellular (EC)-SOD] occur. Human manganese superoxide dismutase (MnSOD), isolated from liver is composed of 22 kDa subunits each containing one Mn atom, while SOD from bovine erythrocyte has a molecular weight of 32.5 kDa. Superoxide Dismutase occurs in high concentrations in brain, liver, heart, erythrocytes and kidney.

Superoxide Dismutase (SOD) or CuZn-SOD (SOD1), a cytoplasmic and mitochondrial intermembrane space protein is located on human chromosome 21q22. It belongs to superoxide dismutase multigene family.

Immunogen

recombinant human copper-zinc superoxide dismutase (Cu-Zn-SOD).

Application

Anti-Superoxide Dismutase (SOD) antibody has been used in immunohistochemistry and Cu-Zn SOD detection via ELISA.[1]

Biochem/physiol Actions

Superoxide Dismutase (SOD) appear to protect cells against reactive free radicals by scavenging the superoxide radicals produced by ionization radiation or through other mechanisms. SOD have been proposed as clinically useful for a wide variety of applications including prevention of oncogenesis, tumor promotion, tumor invasiveness, radiation damage, reduction of the cytotoxic and cardiotoxic effects of anticancer drugs, as a measure against the aging process and as anti-inflammatory agents.

Superoxide Dismutase (SOD) or CuZn-SOD (SOD1) mutations results in amyotrophic lateral sclerosis It acts as a mediator of the HMF (hypomagnetic field) effect.

The antibody recognizes natural and recombinant human-Cu-Zn-SOD, human placental SOD, and human erythrocyte SOD using direct capture or competitive ELISA. Cross-reactivity has been observed with human liver and salivary gland, rat salivary gland, pheochromocytoma cell line (PC12), and dog salivary gland. No reactivity was observed with SOD from bovine erythrocytes, kidney, and liver; dog erythrocytes; Bacillus stearothermophilus; E. coli, or horseradish.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

1 of 1

This Item	S1450	S5069	SAB1406464
Sigma-Aldrich S2147 Monoclonal Anti-Superoxide Dismutase (SOD) antibody produced in mouse	Sigma-Aldrich S1450 Anti-Superoxide Dismutase (MnSOD) (DD-17)−Cy3 antibody produced in rabbit	Sigma-Aldrich S5069 Anti-Superoxide Dismutase (MnSOD) (DD-17) antibody produced in rabbit	Sigma-Aldrich SAB1406464 Anti-SOD1 antibody produced in mouse
Gene Information human ... SOD1(6647) rat ... Sod1(24786)	Gene Information human ... SOD2(6648)	Gene Information human ... SOD2(6648) rat ... Sod2(24787)	Gene Information human ... SOD1(6647)
conjugate unconjugated	conjugate CY3 conjugate	conjugate unconjugated	conjugate unconjugated
clone SD-G6, monoclonal	clone polyclonal	clone polyclonal	clone polyclonal
species reactivity canine, human, rat	species reactivity human, rat, mouse	species reactivity rat, human	species reactivity human
antibody form ascites fluid	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin
biological source mouse	biological source rabbit	biological source rabbit	biological source mouse

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Global Trade Item Number

SKU	GTIN
S2147-.2ML	04061838107466

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