S2147
Monoclonal Anti-Superoxide Dismutase (SOD) antibody produced in mouse
clone SD-G6, ascites fluid
Synonyme(s) :
Anti-ALS, Anti-ALS1, Anti-HEL-S-44, Anti-hSod1, Anti-IPOA, Anti-SOD, Anti-STAHP, Anti-homodimer
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| À vous/Référence | Disponibilité | Prix |
|---|---|---|
0.2 mL | Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit. | 508,00 € 431,80 € |
A propos de cet article
Conjugate:
unconjugated
Clone:
SD-G6, monoclonal
Application:
ELISA (i)
Citations:
23
431,80 €
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Laissez-nous vous aiderbiological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
SD-G6, monoclonal
contains
15 mM sodium azide
species reactivity
canine, human, rat
technique(s)
indirect ELISA: 1:300
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SOD1(6647)
rat ... Sod1(24786)
General description
Monoclonal Anti-Superoxide Dismutase (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Superoxide Dismutase (SOD) is a family of metalloenzymes widely distributed in both plants and animals. In mammalian tissues, three types of superoxide dismutase [Cu-Zn-SOD, Mn-SOD, extracellular (EC)-SOD] occur. Human manganese superoxide dismutase (MnSOD), isolated from liver is composed of 22 kDa subunits each containing one Mn atom, while SOD from bovine erythrocyte has a molecular weight of 32.5 kDa. Superoxide Dismutase occurs in high concentrations in brain, liver, heart, erythrocytes and kidney.
Superoxide Dismutase (SOD) or CuZn-SOD (SOD1), a cytoplasmic and mitochondrial intermembrane space protein is located on human chromosome 21q22. It belongs to superoxide dismutase multigene family.
Immunogen
recombinant human copper-zinc superoxide dismutase (Cu-Zn-SOD).
Application
Anti-Superoxide Dismutase (SOD) antibody has been used in immunohistochemistry and Cu-Zn SOD detection via ELISA.[1]
Biochem/physiol Actions
Superoxide Dismutase (SOD) appear to protect cells against reactive free radicals by scavenging the superoxide radicals produced by ionization radiation or through other mechanisms. SOD have been proposed as clinically useful for a wide variety of applications including prevention of oncogenesis, tumor promotion, tumor invasiveness, radiation damage, reduction of the cytotoxic and cardiotoxic effects of anticancer drugs, as a measure against the aging process and as anti-inflammatory agents.
Superoxide Dismutase (SOD) or CuZn-SOD (SOD1) mutations results in amyotrophic lateral sclerosis It acts as a mediator of the HMF (hypomagnetic field) effect.
The antibody recognizes natural and recombinant human-Cu-Zn-SOD, human placental SOD, and human erythrocyte SOD using direct capture or competitive ELISA. Cross-reactivity has been observed with human liver and salivary gland, rat salivary gland, pheochromocytoma cell line (PC12), and dog salivary gland. No reactivity was observed with SOD from bovine erythrocytes, kidney, and liver; dog erythrocytes; Bacillus stearothermophilus; E. coli, or horseradish.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
1 of 1
Cet article | |||
|---|---|---|---|
| Gene Information human ... SOD1(6647) | Gene Information human ... SOD1(6647) | Gene Information human ... SOD1(6647) | Gene Information human ... SOD2(6648) |
| species reactivity canine, human, rat | species reactivity rat, human, canine, mouse | species reactivity human | species reactivity human, rat, mouse |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate CY3 conjugate |
| biological source mouse | biological source goat | biological source mouse | biological source rabbit |
| antibody form ascites fluid | antibody form affinity isolated antibody | antibody form purified immunoglobulin | antibody form affinity isolated antibody |
| clone SD-G6, monoclonal | clone polyclonal | clone 10D5, monoclonal | clone polyclonal |
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Classe de stockage
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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