Salbutamol hemisulfate is not an anticholinergic. This compound is a β2-Adrenergic receptor agonist.
S5013
Salbutamol hemisulfate salt
≥98%
Synonym(s):
α-([t-Butylamino]methyl)-4-hydroxy-m-xylene-α,α′-diol, Albuterol
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25 mg | Available to ship TODAYfromMILWAUKEE | $88.40 |
50 mg | Available to ship TODAYfromMILWAUKEE | $145.00 |
100 mg | Check Cart for Availability | $243.00 |
250 mg | Available to ship TODAYfromMILWAUKEE | $327.00 $277.95 |
About This Item
Linear Formula:
C13H21NO3 · 1/2H2SO4
CAS Number:
Molecular Weight:
288.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
256-916-8
MDL number:
Assay:
≥98%
Quality Segment
assay
≥98%
solubility
1 M NaOH: 50 mg/ml, clear to slightly hazy, yellow-green
originator
GlaxoSmithKline
SMILES string
OS(O)(=O)=O.CC(C)(C)NCC(O)c1ccc(O)c(CO)c1.CC(C)(C)NCC(O)c2ccc(O)c(CO)c2
InChI
1S/2C13H21NO3.H2O4S/c2*1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h2*4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)
InChI key
BNPSSFBOAGDEEL-UHFFFAOYSA-N
Gene Information
human ... ADRB2(154)
Application
Salbutamol hemisulfate salt was used as standard in analysis of fortified meat for LABA content using ELISA kits.3 It was used to study the response of prostaglandin 2α to various β-adrenergic agonists in cultured bovine endometrial cells.4
Salbutamol hemisulfate salt has been used as reference standards of drugs for the validation of β-agonist residue.
Biochem/physiol Actions
β2-Adrenergic receptor agonist.
Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).1 Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.2
Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP). Salbutamol is particularly effective in treatment of asthma as it provides immediate relief. Salbutamol is one of the most popular short-acting BA (SABA). It is useful in treating the symptoms of EIB (exercise induced bronchospasm).
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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This Item | |||
|---|---|---|---|
| description ≥98% | description Pharmaceutical Secondary Standard; Certified Reference Material | description European Pharmacopoeia (EP) Reference Standard | description United States Pharmacopeia (USP) Reference Standard |
| assay ≥98% | assay - | assay - | assay - |
| Quality Level 200 | Quality Level 300 | Quality Level - | Quality Level - |
| solubility 1 M NaOH: 50 mg/ml, clear to slightly hazy, yellow-green | solubility - | solubility - | solubility - |
| originator GlaxoSmithKline | originator - | originator - | originator - |
| Gene Information human ... ADRB2(154) | Gene Information human ... ADRB2(154) | Gene Information human ... ADRB2(154) | Gene Information human ... ADRB2(154) |
signalword
Warning
hcodes
Hazard Classifications
Carc. 2 - Repr. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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