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Monoclonal Anti-Synaptophysin antibody produced in mouse

Name: Monoclonal Anti-Synaptophysin antibody produced in mouse
Brand: SIGMA
Price: 763 USD
Availability: InStock

clone SVP-38, ascites fluid

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Synonym(s):

Synaptophysin Antibody, Synaptophysin Antibody - Monoclonal Anti-Synaptophysin antibody produced in mouse

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Size/SKU	Availability	Price
0.2 mL	Available to ship TODAYfromMILWAUKEE	$763.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00164741

Conjugate:

unconjugated

Clone:

SVP-38, monoclonal

Application:

ELISA (i), IHC (f), IHC (p), WB

Citations:

306

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

SVP-38, monoclonal

mol wt

antigen 38 kDa

contains

15 mM sodium azide

species reactivity

pig, rat, human, guinea pig

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunohistochemistry (frozen sections): 1:200 using rat cerebellum, indirect ELISA: suitable, western blot: suitable

isotype

IgG1

UniProt accession no.

P08247

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SYP(6855)
rat ... Syp(24804)

Description

General description

Synaptophysin (SYP) is an integral membrane glycoprotein of 38,000 Da and it has four membrane-spanning domains. Synaptophysin is localized to neurons, neuromuscular junctions, paraganglia cells, hypophysis, pancreatic islet cells, and adrenal cells. SYP gene is mapped to human chromosome Xp11.23. Monoclonal Anti-Synaptophysin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

Immunogen

Rat retina synaptosome.

Application

Monoclonal Anti-Synaptophysin antibody has been used in western blotting.

Biochem/physiol Actions

Labels synaptophysin in neurons, neuromuscular junctions, benign and malignant neural tumors, paraganglia cells, hypophysis, pancreatic islet cells, and adrenal cells.

Synaptophysin participates in calcium dependent exocytosis. The antibody detects synaptophysin in many types of benign and malignant neural and epithelial neuroendocrine neoplasms. It is widely used as a potential marker to study the circulation of synapses in the brain and to discover the basic features of the life cycle of synaptic vesicles (SVs).

Physical form

Monoclonal Anti-Synaptophysin is provided as ascites fluid containing 0.1% sodium azide.

Preparation Note

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB4200544	MABN1193	SAB4502906
Sigma-Aldrich S5768 Monoclonal Anti-Synaptophysin antibody produced in mouse	Sigma-Aldrich SAB4200544 Anti-Synaptophysin antibody, Mouse monoclonal	Sigma-Aldrich MABN1193 Anti-Synaptophysin Antibody, clone 10F6.1	Sigma-Aldrich SAB4502906 Anti-Synaptophysin antibody produced in rabbit
description clone SVP-38, ascites fluid	description clone SVP-38, purified from hybridoma cell culture	description clone 10F6.1, from mouse	description affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source mouse	biological source mouse	biological source mouse	biological source rabbit
species reactivity pig, rat, human, guinea pig	species reactivity rat, human	species reactivity mouse, rat, human	species reactivity mouse, rat, human
clone SVP-38, monoclonal	clone SVP-38, monoclonal	clone 10F6.1, monoclonal	clone polyclonal
antibody form ascites fluid	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form affinity isolated antibody
Gene Information human ... SYP(6855) rat ... Syp(24804)	Gene Information human ... SYP(6855)	Gene Information human ... SYP(6855) rat ... Syp(24804)	Gene Information human ... SYP(6855)

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Storage Class

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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