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Anti-HVCN1 antibody produced in rabbit

Name: Anti-HVCN1 antibody produced in rabbit
Brand: SIGMA
Price: 601 USD
Availability: InStock

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-HV1, Anti-Hydrogen voltage-gated channel 1, Anti-VSOP, Anti-Voltage sensor domain-only protein

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Size/SKU	Availability	Price
100 μg	Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$601.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

$601.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 30 kDa

species reactivity

rat, human, mouse

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

NP_115745

UniProt accession no.

Q96D96

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HVCN1(84329)

Description

General description

Hydrogen voltage gated channel 1 (HVCN1) is a voltage gated proton channel and is needed for efflux of intracellular acid. The gene encoding it is localized on human chromosome 12q24.11.

Immunogen

HVCN1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human HVCN1.

Biochem/physiol Actions

Hydrogen voltage gated channel 1 (HVCN1) modulates insulin secretion by participating in Ca²⁺ homeostasis. In mice, the channel is involved in superoxide generation, bacterial removal from granulocytes and neutrophils and superoxide-associated B-cell receptor (BCR) signaling. HVCN1 might be associated with BCR-mediated B-cell malignancies.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500536.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	HPA039329	H3038	HPA019195
Sigma-Aldrich SAB3500536 Anti-HVCN1 antibody produced in rabbit	Sigma-Aldrich HPA039329 Anti-HVCN1 antibody produced in rabbit	Sigma-Aldrich H3038 Anti-HCN1 antibody produced in rabbit	Sigma-Aldrich HPA019195 Anti-HCN1 antibody produced in rabbit
description affinity isolated antibody, buffered aqueous solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description affinity isolated antibody, lyophilized powder	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
technique(s) immunohistochemistry: suitable, indirect ELISA: suitable, immunofluorescence: suitable, western blot: suitable	technique(s) immunohistochemistry: 1:20- 1:50	technique(s) western blot: 1:200-1:400 using rat brain membranes, immunocytochemistry: 1:300 using rat dorsal ganglion primary culture, immunohistochemistry: suitable using mouse cerebellum frozen sections	technique(s) immunoblotting: 0.04-0.4 μg/mL, immunohistochemistry: 1:200-1:500

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Storage Class

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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