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Anti-Neutrophil Elastase antibody, Rabbit monoclonal

Name: Anti-Neutrophil Elastase antibody, Rabbit monoclonal
Brand: SIGMA
Price: 416 USD
Availability: InStock

clone SP203, recombinant, expressed in proprietary host, affinity isolated antibody

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Size/SKU	Availability	Price
100 μL	Check Cart for Availability	$416.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

SP203, monoclonal

Application:

IHC

Citations:

$416.00

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Properties

biological source

rabbit

Quality Segment

100

recombinant

expressed in proprietary host

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP203, monoclonal

species reactivity

human (tested)

technique(s)

immunohistochemistry: 1:100

isotype

IgG

UniProt accession no.

P08246

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... ELANE(1991)

Description

General description

Neutrophil elastase (NE) is a monomeric protein, encoded by the gene mapped to human chromosome 19p13.3. The protein has a molecular mass of 25 kDa and is mainly present in the neutrophil granules (located in the neutrophil cytoplasm).

Neutrophil elastase is a serine proteinase synthesized by promyelocytes and promonocytes. It is secreted by neutrophils to degrade extracellular matrix, and to destroy bacteria. It is used as a marker for myeloid leukemia cells.

Immunogen

Synthetic peptide from human neutrophil elastase protein.

Biochem/physiol Actions

Neutrophil elastase (NE) is a key driver of inflammation in many cardiopulmonary and systemic inflammatory and autoimmune conditions. The encoded protein catalyzes the cleavage of tyrosyl-tRNA synthetase to produce cytokine domains that stimulates neutrophil chemotaxis. In addition, NE also facilitates the secretion of the neutrophil chemoattractant, interleukin-8 from endothelial cells.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB1305716	MABS461	SAB5703017
Sigma-Aldrich SAB5500151 Anti-Neutrophil Elastase antibody, Rabbit monoclonal	Sigma-Aldrich SAB1305716 ANTI-NEUTROPHIL ELASTASE(N-TERMINAL) antibody produced in rabbit	Sigma-Aldrich MABS461 Anti-Neutrophil Elastase Antibody, clone AHN-10	Sigma-Aldrich SAB5703017 Anti-Neutrophil Elastase (ELANE) Antibody, clone 8X4E6, Rabbit Monoclonal
description clone SP203, recombinant, expressed in proprietary host, affinity isolated antibody	description affinity isolated antibody, buffered aqueous solution	description clone AHN-10, from mouse	description -
biological source rabbit	biological source rabbit	biological source mouse	biological source rabbit
clone SP203, monoclonal	clone polyclonal	clone AHN-10, monoclonal	clone 8X4E6, monoclonal
species reactivity human (tested)	species reactivity human	species reactivity human	species reactivity mouse
Gene Information human ... ELANE(1991)	Gene Information human ... ELANE(1991)	Gene Information human ... ELANE(1991)	Gene Information human ... ELANE(1991)
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form -
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated

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Storage Class

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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