SCP0158
Granzyme B Substrate
≥95% (HPLC), lyophilized
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Usually ships in 2 weeks. | $230.00 |
About This Item
Empirical Formula (Hill Notation):
C32H41N5O11
Molecular Weight:
671.69
UNSPSC Code:
12352204
NACRES:
NA.32
$230.00
Usually ships in 2 weeks.
Product Name
Granzyme B Substrate,
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥85%
storage condition
protect from light
storage temp.
−20°C
Application
Granzyme B Substrate (Ac-IEPD-AMC) is a fluorogenic substrate for the detection and assay of caspase 8 and granzyme B which is involved in the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Biochem/physiol Actions
Granzymes belongs to serine proteinase family enzymes and it localizes along with perforin in granules. It is predominant in cytotoxic T cells. Granzyme B induces caspases dependent and independent cell death. It possesses specific cleavage action at aspartate residue in the substrate.
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This Item | |||
|---|---|---|---|
| description - | description - | description - | description - |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) |
| form lyophilized | form lyophilized | form lyophilized | form lyophilized |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| storage condition protect from light | storage condition protect from light | storage condition protect from light | storage condition protect from light |
| composition Peptide Content, ≥85% | composition Peptide Content, ≥65% | composition Peptide Content, ≥75% | composition Peptide Content, ≥85% |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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