SCP0216
Plasminogen Activator Substrate
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| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Usually ships in 2 weeks. | $225.00 |
About This Item
Empirical Formula (Hill Notation):
C28H41N7O5
Molecular Weight:
555.67
NACRES:
NA.32
UNSPSC Code:
12352202
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥80%
storage condition
protect from light
storage temp.
−20°C
Application
Plasminogen Activator Substrate has been used as a fluorogenic thrombin substrate to measure the fluorescence released by cleavage of the thrombin substrate to assess the functional activity of the mannose-binding lectin–mannose-associated serine protease (MBL-MASP) complex.
Plasminogen Activator is a serine protease that coverts plasminogen into plasmin. Plasminogen activator may be detected using VGR peptide substrates such a BOC-VGR-βNA and Boc-Val-Gly-Arg-AMC (VGR).
Biochem/physiol Actions
Plasminogen activator (PA) is used to cure life-threatening coronary and cerebrovascular blockages. The important role of the PA system is to convert the inactive plasminogen to plasmin. However, it also plays a vital role in embryogenesis, cell migration, wound healing, inflammatory response, and apoptotic cell death. The PA system is also involved in tumor growth, angiogenesis, tumor cell invasion, migration, and metastasis in cancer patients.
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This Item | |||
|---|---|---|---|
| description - | description ≥95% (HPLC), solid | description - | description - |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay - | assay - |
| form lyophilized | form solid | form lyophilized powder | form - |
| storage condition protect from light | storage condition - | storage condition - | storage condition - |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| composition Peptide Content, ≥80% | composition - | composition - | composition - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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