SML0269
Nitisinone
≥95% (HPLC), 4-Hydroxyphenylpyruvate oxidase inhibitor, powder
Synonym(s):
2-(2-Nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione, 2-[2-Nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione, NTBC, Nitisone, SC 0735
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Available to ship TODAYfromMILWAUKEE | $124.00 |
50 mg | Check Cart for Availability | $486.00 |
About This Item
Product Name
Nitisinone, ≥95% (HPLC)
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to brown
solubility
DMSO: ≥5 mg/mL
storage temp.
−20°C
SMILES string
[O-][N+](=O)c1cc(ccc1C(=O)C2C(=O)CCCC2=O)C(F)(F)F
InChI
1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,12H,1-3H2
InChI key
OUBCNLGXQFSTLU-UHFFFAOYSA-N
Gene Information
human ... HPD(3242)
Application
- to induce liver injury
- to treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenase
- in supplemented water to block the accumulation of toxic metabolites in human hepatocyte engrafted mice
- to study its effect on bacterial pyomelanin production
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥95% (HPLC) | description Pharmaceutical Secondary Standard; Certified Reference Material | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form - | form powder | form powder |
| assay ≥95% (HPLC) | assay - | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 300 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. -10 to -25°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: ≥5 mg/mL | solubility - | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 10 mg/mL, clear |
| color white to brown | color - | color white to beige | color light yellow to dark yellow |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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