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SML0378

Ralfinamide mesylate

≥98% (HPLC)

Synonym(s):

(2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate

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Size/SKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$143.00
50 mg

Available to ship TODAYfromMILWAUKEE

$379.00

About This Item

Empirical Formula (Hill Notation):
C17H19FN2O2 · CH3SO3H
CAS Number:
Molecular Weight:
398.45
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$143.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D 10 to 15° (c=1 HOAc)

color

white to beige

solubility

H2O: >15 mg/mL

storage temp.

2-8°C

SMILES string

CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O

InChI

1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-6-8-15(9-7-13)22-11-14-4-2-3-5-16(14)18;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1

InChI key

CHQVNINIGBRKGZ-YDALLXLXSA-N

Biochem/physiol Actions

Ralfinamide is a mixed sodium and N-type calcium channel blocker.
Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependent, with higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents.

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
SML0025SML2739SML2657
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: >15 mg/mL

solubility

H2O: ≥15 mg/mL

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to tan

color

white to beige

color

white to beige


pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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