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SML0500

GSK334429 hydrochloride

≥98% (HPLC)

Synonym(s):

1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride

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Size/SKUAvailabilityPrice
5 mg
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$145.00
$123.25

About This Item

Empirical Formula (Hill Notation):
C20H29F3N4O · xHCl
CAS Number:
Molecular Weight:
398.47 (free base basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$123.25

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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 5 mg/mL (clear solution)

storage temp.

2-8°C

SMILES string

Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F

InChI

1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H

InChI key

RCZVWLOXPFGZDD-UHFFFAOYSA-N

Biochem/physiol Actions

GSK334429 is a selective histamine H3 receptor antagonist.
GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Store desiccated; dry room.

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This Item
SML0766SML2169SML2331
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

storage condition

desiccated

storage condition

desiccated

solubility

H2O: 5 mg/mL (clear solution)

solubility

DMSO: 15 mg/mL, clear

solubility

H2O: 2 mg/mL, clear (warmed)

solubility

DMSO: 2 mg/mL, clear


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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