SML0738
RORγ Activator 1b
≥98% (HPLC)
Synonym(s):
N-(4,6-Dimethyl-2-benzothiazolyl)-3-methyl-2-thiophenecarboxamide
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| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Available to ship TODAYfromMILWAUKEE | $318.00 |
About This Item
Empirical Formula (Hill Notation):
C15H14N2OS2
CAS Number:
Molecular Weight:
302.41
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
RORγ Activator 1b binds to the retinoid-related orphan receptor RORγ and induces IL-17 reporter gene expression with an EC50 of 0.1 μM. The compound RORγ Activator 1b enhances differentiation of CD4+ T cells to IL-17-secreting cells with a maximum effect of 220 percent of control at 3 μM.
RORγ Activator 1b binds to the retinoid-related orphan receptor RORγ and induces IL-17 reporter gene expression.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description The RORα/γ Agonist, SR1078 controls the biological activity of RORα/γ. This small molecule/inhibitor is primarily used for Biochemicals applications. | description clone 6F3.1, from mouse | description Chemicon®, from rabbit |
| assay ≥98% (HPLC) | assay ≥99% (HPLC) | assay - | assay - |
| form powder | form solid | form - | form - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. - | storage temp. - |
| solubility DMSO: 20 mg/mL, clear | solubility - | solubility - | solubility - |
| color white to beige | color white | color - | color - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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