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SML1291

Frovatriptan succinate monohydrate

≥97% (HPLC)

Synonym(s):

Frovatriptan succinate, R-(+) 3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole monosuccinate monohydrate

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Size/SKUAvailabilityPrice
10 mg
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$149.00

About This Item

Empirical Formula (Hill Notation):
C14H17N3O · C4H6O4 · H2O
CAS Number:
Molecular Weight:
379.41
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥97% (HPLC)
Form:
powder
Storage condition:
desiccated

$149.00


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Quality Segment

assay

≥97% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC(CCC(O)=O)=O.NC(C(C=C1)=CC2=C1NC3=C2C[C@H](NC)CC3)=O.O

InChI

1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/t9-;;/m1../s1

InChI key

CUETXFMONOSVJA-KLQYNRQASA-N

Gene Information

Biochem/physiol Actions

Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.
Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist.
During migraine condition, frovatriptan succinate monohydrate acts on extra cerebral, intracranial arteries and prevent excessive dilation of these vessels.

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This Item
12864131286402BP950
description

≥97% (HPLC)

description

United States Pharmacopeia (USP) Reference Standard

description

United States Pharmacopeia (USP) Reference Standard

description

British Pharmacopoeia (BP) Reference Standard

assay

≥97% (HPLC)

assay

-

assay

-

assay

-

form

powder

form

-

form

-

form

solid

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

−20°C

solubility

H2O: 20 mg/mL, clear

solubility

-

solubility

-

solubility

-

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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