Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $64.80 $67.10 |
25 mg | Check Cart for Availability | $263.00 $223.55 |
About This Item
Empirical Formula (Hill Notation):
C18H20ClN3O
CAS Number:
Molecular Weight:
329.82
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(NC1=CC=CC=C1Cl)CN(CC2)CCN2C3=CC=CC=C3
InChI
1S/C18H20ClN3O/c19-16-8-4-5-9-17(16)20-18(23)14-21-10-12-22(13-11-21)15-6-2-1-3-7-15/h1-9H,10-14H2,(H,20,23)
InChI key
PTAUSEMXADGRBI-UHFFFAOYSA-N
Biochem/physiol Actions
51164 is a neuron penetrant, potent and selective positive allosteric modulator of TRPC6 channels that activates neuronal store-operated calcium entry (nSOCE) in the hippocampal neurons spines. 51164 fully rescues mushroom spines in Aβ42-treated neurons. It restores long-term potentiation (LTP) deficit in 6 months old hippocampal slices from 5xFAD mouse model.
neuron penetrant, potent and selective positive allosteric modulator of TRPC6 channels that activates nSOCE in the hippocampal neurons spines
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description affinity isolated antibody, lyophilized powder | description affinity isolated antibody | description Chemicon®, from rabbit |
| assay ≥98% (HPLC) | assay - | assay - | assay - |
| form powder | form lyophilized powder | form buffered aqueous solution | form - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.



