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SML2636

Sb4

≥98% (HPLC)

Synonym(s):

2-[[(4-Bromophenyl)methyl]thio]benzoxazole, BMP signaling agonist Sb4

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Size/SKUAvailabilityPrice
5 mg
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$94.40
25 mg
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$307.00

About This Item

Empirical Formula (Hill Notation):
C14H10BrNOS
CAS Number:
100874-08-6
Molecular Weight:
320.20
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD01603921
Assay:
≥98% (HPLC)
Form:
powder

$94.40

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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

BrC1=CC=C(CSC2=NC3=C(C=CC=C3)O2)C=C1

InChI

1S/C14H10BrNOS/c15-11-7-5-10(6-8-11)9-18-14-16-12-3-1-2-4-13(12)17-14/h1-8H,9H2

InChI key

JDVOIBFEFVKUPL-UHFFFAOYSA-N

Biochem/physiol Actions

Cell penetrant, potent bone morphogenetic protein (BMP) signaling agonist that rapidly activate BMP in human renal cells (HEK293)
Sb4 is a cell penetrant, potent bone morphogenetic protein (BMP) signaling agonist that rapidly activate BMP in human renal cells (HEK293). Sb4 activates BMP by stabilization of intracellular p-SMAD-1/5/9. Apparently activation of the BMP pathway by sb4 cannot be reversed by inhibition of Noggin or type I BMP kinase inhibitors

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This Item
203642B2680GF166
Sb4 ≥98% (HPLC)

Sigma-Aldrich

SML2636

Sb4

BMP-4, Human, Recombinant, E. coli

Sigma-Aldrich

203642

BMP-4, Human, Recombinant, E. coli

Bone Morphogenetic Protein 4 human >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

Sigma-Aldrich

B2680

Bone Morphogenetic Protein 4 human

BMP-2 Protein, Human Recombinant The Human Bone morphogenetic protein 2 (or BMP-2 protein) is a member of the BMP protein subgroup of the TGFβ superfamily.

Sigma-Aldrich

GF166

BMP-2 Protein, Human Recombinant

description

≥98% (HPLC)

description

-

description

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

description

The Human Bone morphogenetic protein 2 (or BMP-2 protein) is a member of the BMP protein subgroup of the TGFβ superfamily.

assay

≥98% (HPLC)

assay

-

assay

>95% (SDS-PAGE)

assay

>98% (SDS-PAGE and HPLC)

form

powder

form

-

form

lyophilized powder

form

-

storage temp.

2-8°C

storage temp.

-

storage temp.

−20°C

storage temp.

-10 to -25°C

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

-

solubility

-

color

white to beige

color

-

color

-

color

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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